Otto Warburg: The journey towards the seminal discovery of tumor cell bioenergetic reprogramming

Metabolic reprogramming is now regarded as a hallmark of cancer. This phenomenon was first observed at the level of cellular energetics, in the form of very high rates of lactic acid fermentation, not only in anoxia, but also in the presence of oxygen levels that do not compromise respiration. This...

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Bibliographic Details
Published in:	Biochimica et biophysica acta. Molecular basis of disease Vol. 1867; no. 1; p. 165965
Main Author:	Urbano, Ana M.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.01.2021
Subjects:	Aerobic glycolysis Biochemistry - history Cellular Reprogramming Early research career Energy Metabolism Historical perspective History, 20th Century History, 21st Century Lactic Acid - metabolism Metabolic reprogramming Neoplasms - metabolism Oncometabolism Warburg effect Warburg Otto Historical perspective Aerobic glycolysis Oncometabolism Early research career Metabolic reprogramming Warburg effect
ISSN:	0925-4439, 1879-260X, 1879-260X
Online Access:	Get full text
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