Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation

Adipose tissue macrophages are associated with insulin resistance and are linked to changes in the extracellular matrix. To better characterize adipose macrophages, the extracellular matrix, and adipocyte-macrophage interactions, gene expression from adipose tissue and the stromal vascular fraction...

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Bibliographic Details
Published in:	American journal of physiology: endocrinology and metabolism Vol. 299; no. 6; p. E1016
Main Authors:	Spencer, Michael, Yao-Borengasser, Aiwei, Unal, Resat, Rasouli, Neda, Gurley, Catherine M, Zhu, Beibei, Peterson, Charlotte A, Kern, Philip A
Format:	Journal Article
Language:	English
Published:	United States 01.12.2010
Subjects:	Adipose Tissue - metabolism Adipose Tissue - pathology Adult Cell Line Cells, Cultured Coculture Techniques Collagen Type VI - genetics Collagen Type VI - metabolism Cytokines - genetics Cytokines - metabolism Female Fibrosis - genetics Fibrosis - metabolism Fibrosis - pathology Fluorescent Antibody Technique Glucose Intolerance - genetics Glucose Intolerance - metabolism Glucose Intolerance - pathology Humans Inflammation - genetics Inflammation - metabolism Inflammation - pathology Insulin - genetics Insulin - metabolism Insulin Resistance - physiology Macrophages - metabolism Macrophages - pathology Male Middle Aged Obesity - genetics Obesity - metabolism Obesity - pathology Reverse Transcriptase Polymerase Chain Reaction
ISSN:	1522-1555, 1522-1555
Online Access:	Get more information
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