Methylation profile of individuals with sickle cell trait

Sickle cell trait (SCT) is due to heterozygosity for the β-globin sickle cell mutation. SCT recently has been associated with increased risk of various adverse health outcomes. DNA methylation (DNAm) is one potential mechanism by which SCT may impact disease risk. To identify DNAm sites associated w...

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Veröffentlicht in:	Epigenetics Jg. 20; H. 1; S. 2539234
Hauptverfasser:	Vasconcelos, Ana Gabriela, Johnson, Mari, Cai, Yanwei, Hsu, Li, Franceschini, Nora, Auer, Paul L., Kooperberg, Charles, Raffield, Laura M., Reiner, Alex P.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Taylor & Francis 31.12.2025 Taylor & Francis Group
Schlagworte:	Adult beta-Globins - genetics Black or African American - genetics CpG Islands DNA Methylation Epigenesis, Genetic epigenetic age acceleration epigenetic clock Epigenome Female Genome-Wide Association Study Humans Male Middle Aged Sickle cell trait Sickle Cell Trait - genetics White DNA methylation Sickle cell trait epigenetic age acceleration epigenetic clock
ISSN:	1559-2294, 1559-2308, 1559-2308
Online-Zugang:	Volltext
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