Cardiac mast cell regulation of matrix metalloproteinase-related ventricular remodeling in chronic pressure or volume overload

The chronic elevation in ventricular wall stress secondary to ventricular volume or pressure overload leads to structural remodeling of the muscular, vascular and extracellular matrix components of the myocardium. While initially a compensatory response, the progressive hypertrophy and ventricular d...

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Bibliographic Details

Published in:	Cardiovascular research Vol. 69; no. 3; p. 657
Main Authors:	Janicki, Joseph S, Brower, Gregory L, Gardner, Jason D, Forman, Mary F, Stewart, Jr, James A, Murray, David B, Chancey, Amanda L
Format:	Journal Article
Language:	English
Published:	England 15.02.2006
Subjects:	Extracellular Matrix - enzymology Heart Failure - enzymology Humans Mast Cells - metabolism Matrix Metalloproteinases - metabolism Myocardium - immunology Tissue Inhibitor of Metalloproteinases - metabolism Ventricular Pressure Ventricular Remodeling
ISSN:	0008-6363
Online Access:	Get more information
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