Vitamin D deficiency aggravates COVID-19: systematic review and meta-analysis

There is still limited evidence regarding the influence of vitamin D in people with COVID-19. In this systematic review and meta-analysis, we analyze the association between vitamin D deficiency and COVID-19 severity, via an analysis of the prevalence of vitamin D deficiency and insufficiency in peo...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Critical reviews in food science and nutrition Ročník 62; číslo 5; s. 1308 - 1316
Hlavní autoři: Pereira, Marcos, Dantas Damascena, Alialdo, Galvão Azevedo, Laylla Mirella, de Almeida Oliveira, Tarcio, da Mota Santana, Jerusa
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States Taylor & Francis 2022
Taylor & Francis Ltd
Témata:
Adult
Aged
blood serum
Calciferol
Coronavirus
Coronaviruses
COVID-19
COVID-19 infection
elderly
food science
Humans
Meta-analysis
mortality
Observational studies
pandemic
people
SARS-CoV-2
Systematic review
Viral diseases
Vitamin D
Vitamin D Deficiency - complications
Vitamin D Deficiency - epidemiology
Vitamin deficiency
Vitamins
COVID-19
meta-analysis
Coronavirus
pandemic
vitamin D
ISSN:1040-8398, 1549-7852, 1549-7852
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:There is still limited evidence regarding the influence of vitamin D in people with COVID-19. In this systematic review and meta-analysis, we analyze the association between vitamin D deficiency and COVID-19 severity, via an analysis of the prevalence of vitamin D deficiency and insufficiency in people with the disease. Five online databases-Embase, PubMed, Scopus, Web of Science, ScienceDirect and pre-print Medrevix were searched. The inclusion criteria were observational studies measuring serum vitamin D in adult and elderly subjects with COVID-19. The main outcome was the prevalence of vitamin D deficiency in severe cases of COVID-19. We carried out a meta-analysis with random effect measures. We identified 1542 articles and selected 27. Vitamin D deficiency was not associated with a higher chance of infection by COVID-19 (OR = 1.35; 95% CI = 0.80-1.88), but we identified that severe cases of COVID-19 present 64% (OR = 1.64; 95% CI = 1.30-2.09) more vitamin D deficiency compared with mild cases. A vitamin D concentration insufficiency increased hospitalization (OR = 1.81, 95% CI = 1.41-2.21) and mortality from COVID-19 (OR = 1.82, 95% CI = 1.06-2.58). We observed a positive association between vitamin D deficiency and the severity of the disease.
Bibliografie:ObjectType-Article-2
SourceType-Scholarly Journals-1
content type line 14
ObjectType-Feature-3
ObjectType-Evidence Based Healthcare-1
ObjectType-Article-1
ObjectType-Feature-2
content type line 23
ObjectType-Undefined-3
ISSN:1040-8398
1549-7852
1549-7852
DOI:10.1080/10408398.2020.1841090