Biomechanical analysis of the novel S-type dynamic cage by implementation of teaching learning based optimization algorithm - An experimental and finite element study

•Dynamic S-type PEEK cage design achieves lower stress levels at the fusion level and at adjacent disc levels which may reduce the risk of subsidence.•TLBO approaches can be applied for the selection of dynamic cage with best suitable bone graft.•The optimization technique, experimental study and th...

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Vydáno v:Medical engineering & physics Ročník 112; s. 103955
Hlavní autoři: Manickam, Pechimuthu Susai, Ghosh, Goldina, Shetty, Gautam M., Chowdhury, Amit Roy, Roy, Sandipan
Médium: Journal Article
Jazyk:angličtina
Vydáno: England Elsevier Ltd 01.02.2023
Témata:
Benzophenones
Biomechanical Phenomena
Cervical spine
Cervical Vertebrae - surgery
Dynamic cage
Finite Element Analysis
Humans
Intervertebral Disc
Ketones
Optimization
PEEK
Polyethylene Glycols
Polymers
Range of motion
Spinal Fusion - methods
TLBO
CT
TLBO
Range of motion
Dynamic cage
ACDF
PVC
PEEK
Optimization
Cervical spine
FE
ISSN:1350-4533, 1873-4030, 1873-4030
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Shrnutí:•Dynamic S-type PEEK cage design achieves lower stress levels at the fusion level and at adjacent disc levels which may reduce the risk of subsidence.•TLBO approaches can be applied for the selection of dynamic cage with best suitable bone graft.•The optimization technique, experimental study and the finite element simulation suggested that the S-type square and elliptical cage as the best for anterior cervical discectomy and fusion surgery. Anterior Cervical Discectomy and Fusion (ACDF) is the most popular and effective procedure for patients with intervertebral disc degeneration, where the degenerated disc is replaced with an interbody implant (widely known as cage). The design of the cage plays a vital role since it has to provide stability for the anterior cervical column without any side-effects. We designed a novel S-type dynamic cage for C4-C5 level, using Polyetheretherketone (PEEK) material considering four different shapes namely: square, circle, rectangle and elliptical, for the central window to occupy bone graft. The major design constrain for a successful cage is minimized cage stress, in order to avoid subsidence. Finite Element (FE) analysis results revealed that the cage stress values obtained during the physiological motion varied depending upon the shape of the central window provided for bone graft. The objective of this study is to optimize the central window shape using the Teaching Learning Based Optimization (TLBO) algorithm. It was found that square and elliptical shape bone graft cavity resulted in better outcomes. Additional experimental study was also conducted with a six-axis spine simulator. Based on the optimization results, we manufactured two PEEK cage models with square and elliptical shaped central window using additive manufacturing. A prototype model of the C4-C5 level made of Polyvinylchloride (PVC) was used for experiment due to the existing constraints for using a cadaveric model. The experimental results were cross-verified using FE analysis. Thus, we would like to conclude that square and elliptical shape of the central window were the better design factor for our novel dynamic cage.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:1350-4533
1873-4030
1873-4030
DOI:10.1016/j.medengphy.2023.103955