Ultra-fast RP-HPLC-FD-DAD for quantification of total aflatoxins in maize, rice, wheat, peanut and poultry feed without sample clean up, and population exposure risk assessment in Katsina, Nigeria: an optimization study

This study reports the development and validation of a simple, yet efficient method called the ultra-fast reverse phase high-performance liquid chromatography with fluorescence and photodiode array detector (UF-RP-HPLC-FD-DAD) to extract and quantify the total aflatoxin from grains and poultry feed....

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Veröffentlicht in:	Journal of environmental science and health. Part B, Pesticides, food contaminants, and agricultural wastes Jg. 57; H. 7; S. 541 - 553
Hauptverfasser:	Salisu, Baha'uddeen, Anua, Siti Marwanis, Wan Rosli, Wan Ishak, Mazlan, Nurzafirah, Haron, Rosliza
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Taylor & Francis 14.07.2022 Taylor & Francis Ltd
Schlagworte:	Aflatoxin detection Aflatoxins Corn dietary exposure dietary exposure risk assessment environmental science Exposure fluorescence fluorescence detector food contaminant food security Grain Hepatocellular carcinoma hepatoma High-performance liquid chromatography Liquid chromatography Nigeria Optimization Peanuts photodiode array detector Photodiodes Poultry Poultry feed Rice risk Risk assessment Wheat Nigeria photodiode array detector fluorescence detector food contaminant dietary exposure risk assessment Aflatoxin detection food security
ISSN:	0360-1234, 1532-4109, 1532-4109
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Abstract	This study reports the development and validation of a simple, yet efficient method called the ultra-fast reverse phase high-performance liquid chromatography with fluorescence and photodiode array detector (UF-RP-HPLC-FD-DAD) to extract and quantify the total aflatoxin from grains and poultry feed. The proposed method is used to determine the total aflatoxin content in 150 samples of maize, rice, wheat, peanut and poultry feed obtained from open markets in a state in Nigeria. The extent of consumer exposure to aflatoxins and the risk of developing hepatocellular carcinoma (HCC) are evaluated. The UF-RP-HPLC-FD-DAD method was found to be satisfactorily accurate, sensitive and reliable as ascertained by its excellent validation outcomes (R 2 > 0.999, LoD < 0.08 ng g −1 , LoQ < 0.2 ng g −1 , recovery = 90-102%). The aflatoxin levels in food grains and poultry feed samples obtained in this study implied a moderate dietary exposure of between 10.67 and 20.77 ng/kg BW/day, in which the risk of developing HCC was estimated to be between 6.27 and 21.40% per 100,000 adults/year. Hence, greater monitoring of marketed food and feed is required, besides the deployment of strict controls and preventive techniques to minimize the population's exposure to a high dietary level of aflatoxins.
AbstractList	This study reports the development and validation of a simple, yet efficient method called the ultra-fast reverse phase high-performance liquid chromatography with fluorescence and photodiode array detector (UF-RP-HPLC-FD-DAD) to extract and quantify the total aflatoxin from grains and poultry feed. The proposed method is used to determine the total aflatoxin content in 150 samples of maize, rice, wheat, peanut and poultry feed obtained from open markets in a state in Nigeria. The extent of consumer exposure to aflatoxins and the risk of developing hepatocellular carcinoma (HCC) are evaluated. The UF-RP-HPLC-FD-DAD method was found to be satisfactorily accurate, sensitive and reliable as ascertained by its excellent validation outcomes (R2 > 0.999, LoD < 0.08 ng g-1, LoQ < 0.2 ng g-1, recovery = 90-102%). The aflatoxin levels in food grains and poultry feed samples obtained in this study implied a moderate dietary exposure of between 10.67 and 20.77 ng/kg BW/day, in which the risk of developing HCC was estimated to be between 6.27 and 21.40% per 100,000 adults/year. Hence, greater monitoring of marketed food and feed is required, besides the deployment of strict controls and preventive techniques to minimize the population's exposure to a high dietary level of aflatoxins.This study reports the development and validation of a simple, yet efficient method called the ultra-fast reverse phase high-performance liquid chromatography with fluorescence and photodiode array detector (UF-RP-HPLC-FD-DAD) to extract and quantify the total aflatoxin from grains and poultry feed. The proposed method is used to determine the total aflatoxin content in 150 samples of maize, rice, wheat, peanut and poultry feed obtained from open markets in a state in Nigeria. The extent of consumer exposure to aflatoxins and the risk of developing hepatocellular carcinoma (HCC) are evaluated. The UF-RP-HPLC-FD-DAD method was found to be satisfactorily accurate, sensitive and reliable as ascertained by its excellent validation outcomes (R2 > 0.999, LoD < 0.08 ng g-1, LoQ < 0.2 ng g-1, recovery = 90-102%). The aflatoxin levels in food grains and poultry feed samples obtained in this study implied a moderate dietary exposure of between 10.67 and 20.77 ng/kg BW/day, in which the risk of developing HCC was estimated to be between 6.27 and 21.40% per 100,000 adults/year. Hence, greater monitoring of marketed food and feed is required, besides the deployment of strict controls and preventive techniques to minimize the population's exposure to a high dietary level of aflatoxins. This study reports the development and validation of a simple, yet efficient method called the ultra-fast reverse phase high-performance liquid chromatography with fluorescence and photodiode array detector (UF-RP-HPLC-FD-DAD) to extract and quantify the total aflatoxin from grains and poultry feed. The proposed method is used to determine the total aflatoxin content in 150 samples of maize, rice, wheat, peanut and poultry feed obtained from open markets in a state in Nigeria. The extent of consumer exposure to aflatoxins and the risk of developing hepatocellular carcinoma (HCC) are evaluated. The UF-RP-HPLC-FD-DAD method was found to be satisfactorily accurate, sensitive and reliable as ascertained by its excellent validation outcomes (R2 > 0.999, LoD < 0.08 ng g−1, LoQ < 0.2 ng g−1, recovery = 90–102%). The aflatoxin levels in food grains and poultry feed samples obtained in this study implied a moderate dietary exposure of between 10.67 and 20.77 ng/kg BW/day, in which the risk of developing HCC was estimated to be between 6.27 and 21.40% per 100,000 adults/year. Hence, greater monitoring of marketed food and feed is required, besides the deployment of strict controls and preventive techniques to minimize the population’s exposure to a high dietary level of aflatoxins. This study reports the development and validation of a simple, yet efficient method called the ultra-fast reverse phase high-performance liquid chromatography with fluorescence and photodiode array detector (UF-RP-HPLC-FD-DAD) to extract and quantify the total aflatoxin from grains and poultry feed. The proposed method is used to determine the total aflatoxin content in 150 samples of maize, rice, wheat, peanut and poultry feed obtained from open markets in a state in Nigeria. The extent of consumer exposure to aflatoxins and the risk of developing hepatocellular carcinoma (HCC) are evaluated. The UF-RP-HPLC-FD-DAD method was found to be satisfactorily accurate, sensitive and reliable as ascertained by its excellent validation outcomes ( > 0.999, LoD < 0.08 ng g , LoQ < 0.2 ng g , recovery = 90-102%). The aflatoxin levels in food grains and poultry feed samples obtained in this study implied a moderate dietary exposure of between 10.67 and 20.77 ng/kg BW/day, in which the risk of developing HCC was estimated to be between 6.27 and 21.40% per 100,000 adults/year. Hence, greater monitoring of marketed food and feed is required, besides the deployment of strict controls and preventive techniques to minimize the population's exposure to a high dietary level of aflatoxins. This study reports the development and validation of a simple, yet efficient method called the ultra-fast reverse phase high-performance liquid chromatography with fluorescence and photodiode array detector (UF-RP-HPLC-FD-DAD) to extract and quantify the total aflatoxin from grains and poultry feed. The proposed method is used to determine the total aflatoxin content in 150 samples of maize, rice, wheat, peanut and poultry feed obtained from open markets in a state in Nigeria. The extent of consumer exposure to aflatoxins and the risk of developing hepatocellular carcinoma (HCC) are evaluated. The UF-RP-HPLC-FD-DAD method was found to be satisfactorily accurate, sensitive and reliable as ascertained by its excellent validation outcomes (R 2 > 0.999, LoD < 0.08 ng g −1 , LoQ < 0.2 ng g −1 , recovery = 90-102%). The aflatoxin levels in food grains and poultry feed samples obtained in this study implied a moderate dietary exposure of between 10.67 and 20.77 ng/kg BW/day, in which the risk of developing HCC was estimated to be between 6.27 and 21.40% per 100,000 adults/year. Hence, greater monitoring of marketed food and feed is required, besides the deployment of strict controls and preventive techniques to minimize the population's exposure to a high dietary level of aflatoxins. This study reports the development and validation of a simple, yet efficient method called the ultra-fast reverse phase high-performance liquid chromatography with fluorescence and photodiode array detector (UF-RP-HPLC-FD-DAD) to extract and quantify the total aflatoxin from grains and poultry feed. The proposed method is used to determine the total aflatoxin content in 150 samples of maize, rice, wheat, peanut and poultry feed obtained from open markets in a state in Nigeria. The extent of consumer exposure to aflatoxins and the risk of developing hepatocellular carcinoma (HCC) are evaluated. The UF-RP-HPLC-FD-DAD method was found to be satisfactorily accurate, sensitive and reliable as ascertained by its excellent validation outcomes (R ² > 0.999, LoD < 0.08 ng g⁻¹, LoQ < 0.2 ng g⁻¹, recovery = 90–102%). The aflatoxin levels in food grains and poultry feed samples obtained in this study implied a moderate dietary exposure of between 10.67 and 20.77 ng/kg BW/day, in which the risk of developing HCC was estimated to be between 6.27 and 21.40% per 100,000 adults/year. Hence, greater monitoring of marketed food and feed is required, besides the deployment of strict controls and preventive techniques to minimize the population’s exposure to a high dietary level of aflatoxins.
Author	Anua, Siti Marwanis Mazlan, Nurzafirah Salisu, Baha'uddeen Haron, Rosliza Wan Rosli, Wan Ishak
Author_xml	– sequence: 1 givenname: Baha'uddeen orcidid: 0000-0002-0474-1223 surname: Salisu fullname: Salisu, Baha'uddeen organization: Department of Microbiology, Umaru Musa Yar'adua University – sequence: 2 givenname: Siti Marwanis orcidid: 0000-0001-9909-7735 surname: Anua fullname: Anua, Siti Marwanis organization: School of Health Sciences, Health Campus, Universiti Sains Malaysia – sequence: 3 givenname: Wan Ishak orcidid: 0000-0001-7650-0499 surname: Wan Rosli fullname: Wan Rosli, Wan Ishak organization: School of Health Sciences, Health Campus, Universiti Sains Malaysia – sequence: 4 givenname: Nurzafirah orcidid: 0000-0002-8174-5236 surname: Mazlan fullname: Mazlan, Nurzafirah organization: Borneo Marine Research Institute, Universiti Malaysia Sabah, Jalan UMS – sequence: 5 givenname: Rosliza surname: Haron fullname: Haron, Rosliza organization: School of Health Sciences, Health Campus, Universiti Sains Malaysia
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/35531950$$D View this record in MEDLINE/PubMed
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References	CIT0072 CIT0074 CIT0073 CIT0032 CIT0031 CIT0075 CIT0078 Hymery N. (CIT0016) CIT0077 Gurav N. P. (CIT0030) 2018; 17 CIT0070 ICH. (CIT0046) 1996 Namjoo M. (CIT0060) 2016; 45 CIT0035 CIT0079 CIT0038 CIT0037 Adi P. J. (CIT0061) 2018; 2 CIT0039 Sarnoski P. J. (CIT0064) 2015; 1 ICMSF (CIT0036) 2006 CIT0083 CIT0082 CIT0041 CIT0085 CIT0040 CIT0084 CIT0042 CIT0086 CIT0001 CIT0045 CIT0089 CIT0044 CIT0088 CIT0081 Habib M. A. (CIT0009) 2015; 3 CIT0003 CIT0002 CIT0005 CIT0049 CIT0004 Lizárraga-Paulín E. G. (CIT0033) 2012 ICH (CIT0043) 1995 CIT0008 EC No 401 (CIT0048) 2006; 9 CIT0050 CIT0052 CIT0051 CIT0054 CIT0053 CIT0055 Commission EC/657/2002 (CIT0071) 2002 Stanić A. (CIT0007) 2017 CIT0090 Jonathan S. G. (CIT0012) 2010; 9 Ogunleye A. O. (CIT0006) 2015; 04 Dangora D. B. (CIT0010) 2017; 2 CIT0014 CIT0058 CIT0057 Momodu O. (CIT0087) 2016; 7 CIT0015 CIT0059 CIT0018 Bbosa G. S. (CIT0011) 2013 CIT0017 Okigbo R. N. (CIT0076) 2017; 5 Shotwell O. L. (CIT0067) 1981; 64 CIT0063 Johannesburg W. (CIT0034) 2013; 22 CIT0062 CIT0021 CIT0065 CIT0020 CIT0023 Felagha I. (CIT0080) 2016; 6 CIT0022 Lakka S. N. (CIT0056) 2019 CIT0066 CIT0025 Martínez-Miranda M. (CIT0069) 2015; 26 CIT0024 CIT0068 CIT0027 CIT0026 Gachomo E. W. (CIT0013) 2004; 6 CIT0029 CIT0028 FAO (CIT0047) 2004; 81 Rashid N. (CIT0019); 45
References_xml	– ident: CIT0040 – ident: CIT0050 doi: 10.1111/nyas.12396 – volume: 6 start-page: 955 year: 2004 ident: CIT0013 publication-title: Int. J. Agric. Biol. – ident: CIT0086 doi: 10.1016/j.toxrep.2018.08.011 – ident: CIT0021 – ident: CIT0022 doi: 10.1093/ajcn/80.5.1106 – ident: CIT0068 doi: 10.3390/foods9050661 – volume: 7 start-page: 56 year: 2016 ident: CIT0087 publication-title: J. Aquac. Res. Dev. – ident: CIT0031 doi: 10.1016/j.canlet.2009.02.053 – volume: 81 start-page: 1 volume-title: Worldwide Regulations for Mycotoxins in Food and Feed in 2003 year: 2004 ident: CIT0047 – ident: CIT0044 – ident: CIT0078 doi: 10.1080/19393210.2013.823626 – ident: CIT0077 doi: 10.1016/j.ijfoodmicro.2017.03.020 – volume-title: ICH Q 2 (R1) Validation of Analytical Procedures: ICH Harmonised Tripartite Guideline-CPMP/ICH/381/95 year: 1995 ident: CIT0043 – ident: CIT0073 doi: 10.1080/19440049.2011.576436 – ident: CIT0054 – start-page: 1 year: 2002 ident: CIT0071 publication-title: Off. J. Eur. Commun. – start-page: 239 volume-title: Aflatoxins – recent advances and future prospects year: 2013 ident: CIT0011 – volume: 9 start-page: 1 year: 2006 ident: CIT0048 publication-title: Off. J. Eur. Union. – volume: 22 start-page: 305 year: 2013 ident: CIT0034 publication-title: J. Gastrointest. Liver Dis. – ident: CIT0059 doi: 10.3390/toxins12020093 – volume: 5 start-page: 1 year: 2017 ident: CIT0076 publication-title: Integr. Food Nutr. Metab. – ident: CIT0055 doi: 10.1093/chromsci/bmu222 – ident: CIT0039 doi: 10.1080/10826076.2012.745138 – volume: 17 start-page: 126 year: 2018 ident: CIT0030 publication-title: Anal. Chem. An Indian J – volume: 04 start-page: 345 year: 2015 ident: CIT0006 publication-title: Acad. J. Sci – volume-title: Microorganisms in Foods 6: Microbial Ecology of Food Commodities year: 2006 ident: CIT0036 – ident: CIT0037 – ident: CIT0088 doi: 10.1016/S0189-7241(15)30098-9 – start-page: 255 volume-title: Aflatoxins – Biochemistry and molecular biology year: 2012 ident: CIT0033 – ident: CIT0035 doi: 10.1289/ehp.0901388 – ident: CIT0024 doi: 10.1080/00984109708984048 – volume: 2 start-page: 199 year: 2018 ident: CIT0061 publication-title: Food Qual. Saf. – ident: CIT0045 doi: 10.1080/02652030903107906 – volume: 3 start-page: 27 year: 2015 ident: CIT0009 publication-title: Microbiol. Res. Int – ident: CIT0015 doi: 10.31080/ASAG.2019.03.0511 – ident: CIT0029 doi: 10.3920/WMJ2018.2344 – ident: CIT0041 doi: 10.1080/19440049.2010.551547 – ident: CIT0081 – ident: CIT0065 doi: 10.1016/j.chroma.2012.10.040 – ident: CIT0025 doi: 10.1002/path.1711640307 – ident: CIT0002 doi: 10.1016/j.foodcont.2017.01.008 – ident: CIT0066 doi: 10.1016/j.chroma.2009.03.035 – ident: CIT0014 doi: 10.3389/fmicb.2014.00158 – ident: CIT0053 – ident: CIT0005 doi: 10.1046/j.1365-2958.2002.02933.x – start-page: 437 ident: CIT0016 publication-title: Compr. Rev. Food Sciece Food Saf. – ident: CIT0032 – ident: CIT0075 doi: 10.1016/j.foodcont.2012.07.048 – volume-title: Preparation of thiol conjugates of the mycotoxin deoxynivalenol and their occurrence in nature year: 2017 ident: CIT0007 – ident: CIT0084 doi: 10.1155/2018/1308748 – ident: CIT0027 doi: 10.1080/19440049.2013.789558 – volume: 1 start-page: 75 year: 2015 ident: CIT0064 publication-title: J. Food Heal. Sci. – ident: CIT0074 doi: 10.1007/s00217-014-2221-0 – volume: 26 start-page: 797 year: 2015 ident: CIT0069 publication-title: J. Braz. Chem. Soc. – ident: CIT0026 doi: 10.18697/ajfand.16.2750 – ident: CIT0083 doi: 10.1016/j.foodcont.2018.11.049 – start-page: 1 volume-title: Biochemical Analysis Tools – Methods for Bio-Molecules Studies year: 2019 ident: CIT0056 – ident: CIT0058 doi: 10.1016/j.foodcont.2010.09.007 – volume: 6 start-page: 45 year: 2016 ident: CIT0080 publication-title: Nigeria. J. Environ. Earth Sci. – ident: CIT0017 – ident: CIT0018 doi: 10.1080/19393210.2013.777946 – ident: CIT0001 doi: 10.3389/fmicb.2019.02266 – ident: CIT0052 – ident: CIT0042 doi: 10.1155/2018/4650764 – ident: CIT0008 doi: 10.1016/j.ijfoodmicro.2017.05.020 – ident: CIT0062 doi: 10.1002/mnfr.201100764 – ident: CIT0004 – volume-title: International Conference on Harmonization (ICH) of Technical Requirements for the Registration of Pharmaceuticals for Human Use, Validation of Analytical Procedures: Text and Methodology year: 1996 ident: CIT0046 – ident: CIT0049 doi: 10.3390/children4070058 – ident: CIT0072 doi: 10.1080/19440049.2010.514951 – volume: 45 start-page: 905 year: 2016 ident: CIT0060 publication-title: Iran J. Public Heal. – volume: 9 start-page: 1722 year: 2010 ident: CIT0012 publication-title: Electron. J. Environ. Agric. Food Chem. – volume: 64 start-page: 674 year: 1981 ident: CIT0067 publication-title: J. Assoc. Off. Anal. Chem. – ident: CIT0003 doi: 10.3109/15569541003598553 – ident: CIT0082 doi: 10.1016/j.foodcont.2016.10.034 – ident: CIT0020 – volume: 45 ident: CIT0019 publication-title: Pakistan J. Zoology. – ident: CIT0023 doi: 10.1016/0015-6264(71)90080-0 – ident: CIT0085 doi: 10.1007/s12550-018-0337-y – volume: 2 start-page: 47 year: 2017 ident: CIT0010 publication-title: UMYU J. Microbiol. Res. doi: 10.47430/ujmr.1721.008 – ident: CIT0070 doi: 10.1590/S1983-40632014000300003 – ident: CIT0079 doi: 10.1016/j.fct.2018.08.025 – ident: CIT0090 doi: 10.1088/1755-1315/210/1/012018 – ident: CIT0038 doi: 10.21608/nrmj.2020.73438 – ident: CIT0051 – ident: CIT0028 – ident: CIT0063 doi: 10.1002/mnfr.200800145 – ident: CIT0057 doi: 10.1016/j.foodchem.2009.05.082 – ident: CIT0089 doi: 10.47430/ujmr.2052.005
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Snippet	This study reports the development and validation of a simple, yet efficient method called the ultra-fast reverse phase high-performance liquid chromatography...
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SubjectTerms	Aflatoxin detection Aflatoxins Corn dietary exposure dietary exposure risk assessment environmental science Exposure fluorescence fluorescence detector food contaminant food security Grain Hepatocellular carcinoma hepatoma High-performance liquid chromatography Liquid chromatography Nigeria Optimization Peanuts photodiode array detector Photodiodes Poultry Poultry feed Rice risk Risk assessment Wheat
Title	Ultra-fast RP-HPLC-FD-DAD for quantification of total aflatoxins in maize, rice, wheat, peanut and poultry feed without sample clean up, and population exposure risk assessment in Katsina, Nigeria: an optimization study
URI	https://www.tandfonline.com/doi/abs/10.1080/03601234.2022.2073151 https://www.ncbi.nlm.nih.gov/pubmed/35531950 https://www.proquest.com/docview/2691685686 https://www.proquest.com/docview/2661482341 https://www.proquest.com/docview/2718280157
Volume	57
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