Adjuvant 5-fluorouracil and leucovorin with or without interferon alfa-2a in colon carcinoma: National Surgical Adjuvant Breast and Bowel Project protocol C-05

National Surgical Adjuvant Breast and Bowel Project (NSABP) protocol C-03 showed a benefit from leucovorin (LV)-modulated 5-fluorouracil (5-FU) adjuvant therapy (5-FU + LV) in patients with Dukes' stage B or C carcinoma of the colon. Preclinical and clinical phase I/II data suggested that inter...

Full description

Saved in:

Bibliographic Details
Published in:	JNCI : Journal of the National Cancer Institute Vol. 90; no. 23; p. 1810
Main Authors:	Wolmark, N, Bryant, J, Smith, R, Grem, J, Allegra, C, Hyams, D, Atkins, J, Dimitrov, N, Oishi, R, Prager, D, Fehrenbacher, L, Romond, E, Colangelo, L, Fisher, B
Format:	Journal Article
Language:	English
Published:	United States 02.12.1998
Subjects:	Antimetabolites, Antineoplastic - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Chemotherapy, Adjuvant Colonic Neoplasms - drug therapy Colonic Neoplasms - pathology Disease-Free Survival Drug Administration Schedule Female Fluorouracil - administration & dosage Humans Interferon alpha-2 Interferon-alpha - administration & dosage Leucovorin - administration & dosage Male Middle Aged Neoplasm Staging Recombinant Proteins Survival Analysis Treatment Outcome
ISSN:	0027-8874
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!