Tumor lymphangiogenesis and melanoma metastasis

Malignant melanomas of the skin primarily metastasize to lymph nodes, and the detection of sentinel lymph node metastases serves as an important prognostic parameter. There is now compelling evidence that melanomas can induce lymphangiogenesis (growth of lymphatic vessels), mainly at the tumor–strom...

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Bibliographic Details

Published in:	Journal of cellular physiology Vol. 216; no. 2; pp. 347 - 354
Main Authors:	Rinderknecht, Matthias, Detmar, Michael
Format:	Journal Article
Language:	English
Published:	Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.08.2008
Subjects:	Animals Biomarkers, Tumor - metabolism Intercellular Signaling Peptides and Proteins - metabolism Lymph Nodes - pathology Lymphangiogenesis - physiology Lymphatic Metastasis Lymphatic Vessels - metabolism Lymphatic Vessels - pathology Melanoma - diagnosis Melanoma - pathology Prognosis Skin Neoplasms - diagnosis Skin Neoplasms - pathology Vascular Endothelial Growth Factor A - metabolism
ISSN:	0021-9541, 1097-4652, 1097-4652
Online Access:	Get full text
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