A Novel Complexity Algorithm for Quantification of Consciousness Levels

The level of human consciousness is a critical indicator in medicine, essential for the accurate diagnosis of specific conditions such as brain death. This study aims to provide an objective and visual consciousness indicator for medical applications by proposing a new algorithm to quantify consciou...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:IEEE Access Jg. 12; S. 118665 - 118672
Hauptverfasser: Shen, Chengyuan, Mitsukura, Yasue, Cao, Jianting
Format: Journal Article
Sprache:Englisch
Veröffentlicht: IEEE 2024
Institute of Electrical and Electronics Engineers (IEEE)
Schlagworte:
Anesthesia
Approximation algorithms
Complexity theory
Consciousness assessment
D-MaxApEn
Electrical engineering. Electronics. Nuclear engineering
Electrodes
Electroencephalography
Glasgow coma scale
Heuristic algorithms
TK1-9971
White noise
ISSN:2169-3536, 2169-3536
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Abstract The level of human consciousness is a critical indicator in medicine, essential for the accurate diagnosis of specific conditions such as brain death. This study aims to provide an objective and visual consciousness indicator for medical applications by proposing a new algorithm to quantify consciousness. Traditionally, consciousness levels have been qualitatively assessed using scales like the Glasgow Coma Scale (GCS). In this study, we introduce a novel algorithm, termed D-MaxApEn, designed to quantify consciousness. This algorithm was applied to EEG data from four different states: wakefulness, anesthesia, coma, and brain death. Through calculation and analysis, we objectively quantified these four levels of consciousness and validated the effectiveness of this algorithm in a real-time brain death diagnosis system. The results demonstrate the significant potential of this algorithm for the future diagnosis of the level of consciousness. Its use could revolutionize early intervention, improve patient outcomes, and reduce the burden on individuals and healthcare systems.
AbstractList The level of human consciousness is a critical indicator in medicine, essential for the accurate diagnosis of specific conditions such as brain death. This study aims to provide an objective and visual consciousness indicator for medical applications by proposing a new algorithm to quantify consciousness. Traditionally, consciousness levels have been qualitatively assessed using scales like the Glasgow Coma Scale (GCS). In this study, we introduce a novel algorithm, termed D-MaxApEn, designed to quantify consciousness. This algorithm was applied to EEG data from four different states: wakefulness, anesthesia, coma, and brain death. Through calculation and analysis, we objectively quantified these four levels of consciousness and validated the effectiveness of this algorithm in a real-time brain death diagnosis system. The results demonstrate the significant potential of this algorithm for the future diagnosis of the level of consciousness. Its use could revolutionize early intervention, improve patient outcomes, and reduce the burden on individuals and healthcare systems.
Author Shen, Chengyuan
Mitsukura, Yasue
Cao, Jianting
Author_xml – sequence: 1
  givenname: Chengyuan
  orcidid: 0009-0002-2130-5295
  surname: Shen
  fullname: Shen, Chengyuan
  organization: Saitama Institute of Technology, Fukaya, Japan
– sequence: 2
  givenname: Yasue
  surname: Mitsukura
  fullname: Mitsukura, Yasue
  organization: Graduate School of Science and Technology, Keio University, Yokohama, Kanagawa, Japan
– sequence: 3
  givenname: Jianting
  orcidid: 0000-0002-7749-7188
  surname: Cao
  fullname: Cao, Jianting
  email: cao@sit.ac.jp
  organization: Saitama Institute of Technology, RIKEN Center for Advanced Intelligence Project (AIP), Fukaya, Japan
BackLink https://cir.nii.ac.jp/crid/1873680966333831552$$DView record in CiNii
BookMark eNpNkF9LwzAUxYNMcM59An3og6-dSfOn6eMocw6GItPnkKTJzOiakXTivr2tHbL7cO_lcM-Py7kFo8Y3BoB7BGcIweJpXpaLzWaWwYzMMCGUsPwKjDPEihRTzEYX-w2YxriDXfFOovkYLOfJq_82dVL6_aE2P649JfN664Nrv_aJ9SF5P8qmddZp2TrfJN52p03Uzh9jY2JM1qazxztwbWUdzfQ8J-DzefFRvqTrt-WqnK9TTTLWplYrqrjWSua5klIbXuiME2qUshoVqKCWcEkpshZKphXKEaswYZmpoKU8wxOwGriVlztxCG4vw0l46cSf4MNWyNA6XRvBbaVpgVgukSLKIpkpo6xkjCBCMbEdCw8sHXyMwdh_HoKij1YM0Yo-WnGOtnM9Dq7GOaFd3xHPMeOwYAxjzDGitH_0YThzxpgLMMOcUY5_AS4WgnE
CODEN IAECCG
Cites_doi 10.1016/j.pmr.2016.12.003
10.1109/TBME.2006.873543
10.1109/DOCS60977.2023.10294938
10.1016/j.neucom.2012.11.003
10.3389/fncom.2015.00016
10.1109/EMBC.2013.6611202
10.7717/peerj.4817
10.1212/WNL.58.3.349
10.1038/ncpneuro0887
10.3389/fphys.2023.1165450
10.1172/JCI29172
10.1016/j.tics.2016.03.009
10.1016/S0140-6736(74)91639-0
10.1109/TITB.2006.884369
10.1080/02699050902926267
10.1080/00029238.1988.11080272
10.1007/978-3-642-13318-3_44
10.1007/11893011_157
10.1109/tbme.2008.919870
10.1016/S0140-6736(06)68508-5
10.1152/ajpheart.2000.278.6.h2039
10.1109/TBME.2005.862547
10.1097/01.sa.0000318631.05261.66
10.1097/00002727-200102000-00005
10.1097/01.anes.0000264790.07231.2d
10.1186/1741-7015-9-18
10.1016/j.artmed.2009.03.003
10.1038/nrn1789
10.24297/ijct.v16i1.5934
10.1080/09602010443000498
10.1016/S0140-6736(72)90242-5
10.1136/jnnp.57.11.1308
10.1016/j.aenj.2012.06.002
10.1016/j.tins.2009.11.002
10.1073/pnas.88.6.2297
ContentType Journal Article
DBID 97E
ESBDL
RIA
RIE
RYH
AAYXX
CITATION
DOA
DOI 10.1109/ACCESS.2024.3445467
DatabaseName IEEE All-Society Periodicals Package (ASPP) 2005–Present
IEEE Xplore Open Access Journals
IEEE All-Society Periodicals Package (ASPP) 1998–Present
IEEE Xplore Digital Library
CiNii Complete
CrossRef
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
DatabaseTitleList

Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Open Access Full Text
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: RIE
  name: IEEE Xplore Digital Library
  url: https://ieeexplore.ieee.org/
  sourceTypes: Publisher
DeliveryMethod fulltext_linktorsrc
Discipline Engineering
EISSN 2169-3536
EndPage 118672
ExternalDocumentID oai_doaj_org_article_8fdc59167a1b4bf1a2bebfa66414534f
10_1109_ACCESS_2024_3445467
10638658
Genre orig-research
GrantInformation_xml – fundername: JSPS KAKENHI
  grantid: 20H04249
GroupedDBID 0R~
4.4
5VS
6IK
97E
AAJGR
ABAZT
ABVLG
ACGFS
ADBBV
AGSQL
ALMA_UNASSIGNED_HOLDINGS
BCNDV
BEFXN
BFFAM
BGNUA
BKEBE
BPEOZ
EBS
EJD
ESBDL
GROUPED_DOAJ
IPLJI
JAVBF
KQ8
M43
M~E
O9-
OCL
OK1
RIA
RIE
RNS
RYH
AAYXX
CITATION
ID FETCH-LOGICAL-c426t-fcb5b8ccba77baace89c2845ebbfc19195f48a551ff0a6cb1716d3462ed0f5823
IEDL.DBID RIE
ISICitedReferencesCount 0
ISICitedReferencesURI http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=001303373600001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN 2169-3536
IngestDate Fri Oct 03 12:50:30 EDT 2025
Sat Nov 29 04:27:02 EST 2025
Fri Jun 27 00:08:26 EDT 2025
Wed Aug 27 02:02:13 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Language English
License https://creativecommons.org/licenses/by-nc-nd/4.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c426t-fcb5b8ccba77baace89c2845ebbfc19195f48a551ff0a6cb1716d3462ed0f5823
ORCID 0000-0002-7749-7188
0009-0002-2130-5295
OpenAccessLink https://ieeexplore.ieee.org/document/10638658
PageCount 8
ParticipantIDs doaj_primary_oai_doaj_org_article_8fdc59167a1b4bf1a2bebfa66414534f
nii_cinii_1873680966333831552
ieee_primary_10638658
crossref_primary_10_1109_ACCESS_2024_3445467
PublicationCentury 2000
PublicationDate 20240000
2024-01-01
2024-00-00
PublicationDateYYYYMMDD 2024-01-01
PublicationDate_xml – year: 2024
  text: 20240000
PublicationDecade 2020
PublicationTitle IEEE Access
PublicationTitleAbbrev Access
PublicationYear 2024
Publisher IEEE
Institute of Electrical and Electronics Engineers (IEEE)
Publisher_xml – name: IEEE
– name: Institute of Electrical and Electronics Engineers (IEEE)
References ref13
ref35
ref12
ref34
ref15
ref14
ref31
ref30
ref11
ref33
ref10
ref32
ref2
ref1
ref17
ref16
ref19
ref18
ref24
ref23
ref26
ref25
ref20
ref22
ref21
ref28
ref27
ref29
ref8
ref7
ref9
ref4
ref3
ref6
ref5
References_xml – ident: ref2
  doi: 10.1016/j.pmr.2016.12.003
– ident: ref19
  doi: 10.1109/TBME.2006.873543
– ident: ref33
  doi: 10.1109/DOCS60977.2023.10294938
– ident: ref28
  doi: 10.1016/j.neucom.2012.11.003
– ident: ref10
  doi: 10.3389/fncom.2015.00016
– ident: ref14
  doi: 10.1109/EMBC.2013.6611202
– ident: ref26
  doi: 10.7717/peerj.4817
– ident: ref29
  doi: 10.1212/WNL.58.3.349
– ident: ref30
  doi: 10.1038/ncpneuro0887
– ident: ref15
  doi: 10.3389/fphys.2023.1165450
– ident: ref9
  doi: 10.1172/JCI29172
– ident: ref4
  doi: 10.1016/j.tics.2016.03.009
– ident: ref31
  doi: 10.1016/S0140-6736(74)91639-0
– ident: ref34
  doi: 10.1109/TITB.2006.884369
– ident: ref6
  doi: 10.1080/02699050902926267
– ident: ref25
  doi: 10.1080/00029238.1988.11080272
– ident: ref35
  doi: 10.1007/978-3-642-13318-3_44
– ident: ref24
  doi: 10.1007/11893011_157
– ident: ref22
  doi: 10.1109/tbme.2008.919870
– ident: ref1
  doi: 10.1016/S0140-6736(06)68508-5
– ident: ref17
  doi: 10.1152/ajpheart.2000.278.6.h2039
– ident: ref21
  doi: 10.1109/TBME.2005.862547
– ident: ref27
  doi: 10.1097/01.sa.0000318631.05261.66
– ident: ref5
  doi: 10.1097/00002727-200102000-00005
– ident: ref20
  doi: 10.1097/01.anes.0000264790.07231.2d
– ident: ref11
  doi: 10.1186/1741-7015-9-18
– ident: ref12
  doi: 10.1016/j.artmed.2009.03.003
– ident: ref32
  doi: 10.1038/nrn1789
– ident: ref23
  doi: 10.24297/ijct.v16i1.5934
– ident: ref16
  doi: 10.1080/09602010443000498
– ident: ref3
  doi: 10.1016/S0140-6736(72)90242-5
– ident: ref8
  doi: 10.1136/jnnp.57.11.1308
– ident: ref7
  doi: 10.1016/j.aenj.2012.06.002
– ident: ref13
  doi: 10.1016/j.tins.2009.11.002
– ident: ref18
  doi: 10.1073/pnas.88.6.2297
SSID ssj0000816957
Score 2.2998416
Snippet The level of human consciousness is a critical indicator in medicine, essential for the accurate diagnosis of specific conditions such as brain death. This...
SourceID doaj
crossref
nii
ieee
SourceType Open Website
Index Database
Publisher
StartPage 118665
SubjectTerms Anesthesia
Approximation algorithms
Complexity theory
Consciousness assessment
D-MaxApEn
Electrical engineering. Electronics. Nuclear engineering
Electrodes
Electroencephalography
Glasgow coma scale
Heuristic algorithms
TK1-9971
White noise
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV09T8MwELVQxQAD4qOIAkUeGAlNYju2x1BRGFAFEkjdIn9CpZKifkn8e3xJgGwsLBmiSI7fxXf3otN7CF2Gw6codTySlqQRFVRFmnIWMWGpsswSqVRlNsHHYzGZyMeW1RfMhNXywDVwA-GtYaGH4SrRVPtEpdppr7KMJpQR6iH7xly2yFSVg0WSScYbmaEkloN8OAw7CoQwpdeEUlY7y_-Wokqxv7FYCXWmnE5bdWa0j_aaBhHn9YsdoC1XHqLdlmzgEbrL8Xi-cTMMhxkELVefOJ-9zgPPf3vHoQvFT2tVDwFVuOO5x2DMaWDeFVIbfoBRoWUXvYxun4f3UWOIEJlQSFeRN5ppYYxWnGuljBPShPLCnNbeBOIlmadChR7I-1hlRoMUjiU0S52NPRMpOUadcl66E4QlcY5bnoZgJNRrIYjnUluResmIMaSHrr6xKT5q3Yui4guxLGooC4CyaKDsoRvA7-dREK2uboRQFk0oi79C2UNdQL-1XgaOpKKH-iEchZnCNRGcZCIQr4wAuwYFudP_WPwM7cCG6r8r56izWqxdH22bzWq6XFxUX9cXpwLQbg
  priority: 102
  providerName: Directory of Open Access Journals
Title A Novel Complexity Algorithm for Quantification of Consciousness Levels
URI https://ieeexplore.ieee.org/document/10638658
https://cir.nii.ac.jp/crid/1873680966333831552
https://doaj.org/article/8fdc59167a1b4bf1a2bebfa66414534f
Volume 12
WOSCitedRecordID wos001303373600001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVAON
  databaseName: DOAJ Open Access Full Text
  customDbUrl:
  eissn: 2169-3536
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0000816957
  issn: 2169-3536
  databaseCode: DOA
  dateStart: 20130101
  isFulltext: true
  titleUrlDefault: https://www.doaj.org/
  providerName: Directory of Open Access Journals
– providerCode: PRVHPJ
  databaseName: ROAD: Directory of Open Access Scholarly Resources
  customDbUrl:
  eissn: 2169-3536
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0000816957
  issn: 2169-3536
  databaseCode: M~E
  dateStart: 20130101
  isFulltext: true
  titleUrlDefault: https://road.issn.org
  providerName: ISSN International Centre
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1NT9wwEB3BigMcWmhBbAsrHzg2sInt2D5uV0APZQUSlbhF_oRIy6Zaskhc-tvrcQLspYderChKlORNJjPjjN8DOInOpxnzIlOOFhmTTGeGCZ5x6Zh23FGldRKbELOZvLtT1_1i9bQWxnufms_8KW6mf_musSucKoseXqJEpdyETSHKbrHW24QKKkgoLnpmoXyszibTaXyIWAMW7JQyxjsx-ffok0j6e1WVGFoWdb0WWi4-_udN7cKHPockk87oe7DhF59gZ41Z8DNcTsisefZzgv6OnJftC5nM75tl3T48kpiokpuV7vqEkmlIEwhqd1psicWvH_mJ3URP-_Dr4vx2-iPrNRMyG2NtmwVruJHWGi2E0dp6qWyMQNwbE2yszRQPTOqYJoUw1qU1yJbjKCsL78aBy4IewGDRLPwhEEW9F04U0V45C0ZKGoQyThZBcWotHcK3Vyyr3x01RpVKirGqOugrhL7qoR_Cd8T77VDktU47IppV7yaVDM7ymLEKnRtmQq4L403QZclyxikLQ9hHC6xdrwN_CMfRfJWtccyloKWMtVlJsQBHkrkv_zjvK2zjPXZzKkcwaJcrfwxb9rmtn5ajVKDH8erP-Si9bH8B7L_Pfg
linkProvider IEEE
linkToHtml http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1NT9wwEB21UKlwKP0AsbS0PvTY0E1sx_ZxWZVSdVlRiUrcLH-2kWCDliwS_x6Pk9K99NBLFEWJ4rzJZGac8XsAH5PzGcaCKJSnVcEkM4VlghdcemY891QZk8UmxHwuLy_V-bBYPa-FCSHk5rNwhLv5X75v3QqnypKH1yhRKZ_CJkpnDcu1HqdUUENCcTFwC5Vj9XkynabHSFVgxY4oY7yXk_8bfzJN_6CrkoLLomnWgsvJzn8O6yW8GLJIMunN_gqehMVr2F7jFnwDXydk3t6FK4Iej6yX3T2ZXP1ql033-5qkVJX8WJm-Uygbh7SRoHqnw6ZY_P6RGfYT3e7Cz5MvF9PTYlBNKFyKtl0RneVWOmeNENYYF6RyKQbxYG10qTpTPDJpUqIU49jUziJfjqesroIfRy4rugcbi3YR9oEoGoLwokoWK1m0UtIolPWyiopT5-gIPv3BUt_05Bg6FxVjpXvoNUKvB-hHcIx4P56KzNb5QEJTD46iZfSOp5xVmNIyG0tT2WCjqWtWMk5ZHMEuWmDtfj34IzhM5tOuwW0pBa1lqs5qiiU40swd_OO6D_D89OJspmff5t_fwhaOt59heQcb3XIVDuGZu-ua2-X7_LI9AB2S0KE
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+Novel+Complexity+Algorithm+for+Quantification+of+Consciousness+Levels&rft.jtitle=IEEE+access&rft.au=Shen%2C+Chengyuan&rft.au=Mitsukura%2C+Yasue&rft.au=Cao%2C+Jianting&rft.date=2024&rft.pub=IEEE&rft.eissn=2169-3536&rft.volume=12&rft.spage=118665&rft.epage=118672&rft_id=info:doi/10.1109%2FACCESS.2024.3445467&rft.externalDocID=10638658
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2169-3536&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2169-3536&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2169-3536&client=summon