Mortality and causes of death of traumatic spinal cord injury in Finland

Prospective cohort study. To study the mortality rates of TSCI patients compared to matched controls and to examine possible TSCI-related mortality risk factors and causes of death. Oulu and Tampere University Hospital, Finland. All consecutive patients with a new TSCI were included in a prospective...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Spinal cord Ročník 63; číslo 1; s. 24
Hlavní autoři: Johansson, Elina, Koskinen, Eerika, Helminen, Mika, Vainionpää, Aki, Luoto, Teemu M
Médium: Journal Article
Jazyk:angličtina
Vydáno: England 01.01.2025
Témata:
Adolescent
Adult
Aged
Aged, 80 and over
Cause of Death
Female
Finland - epidemiology
Humans
Male
Middle Aged
Pneumonia - mortality
Prospective Studies
Risk Factors
Spinal Cord Injuries - mortality
Young Adult
Finland
ISSN:1476-5624, 1476-5624
On-line přístup:Zjistit podrobnosti o přístupu
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Abstract Prospective cohort study. To study the mortality rates of TSCI patients compared to matched controls and to examine possible TSCI-related mortality risk factors and causes of death. Oulu and Tampere University Hospital, Finland. All consecutive patients with a new TSCI were included in a prospective study (n = 344, 2012-16). All patients were followed until death or the end of 2019. Patients were compared to a control group formed by randomly choosing gender, age, municipality, and calendar time-matched controls (5 controls/TSCI patient). Standardized mortality ratios (SMR) were calculated using general population mortality rates. Mortality information was extracted from the Statistics of Finland (Helsinki, Finland). TSCI patients had an increased mortality (SMR = 2.9) compared with the Finnish population. During the observation period, 26% of TSCI patients and 12% of the matched controls died. Of the TSCI patient deaths, 51% occurred within the first two years postinjury. Increased age, severity of TSCI (as per International SCI Core Data Set) and fall were related to mortality (p < 0.05). The two most common etiologies of death were: circulatory (30%), and pulmonary diseases (28%). Pneumonia was the single most frequent disease leading to death among TSCI patients. During the first years after injury, the mortality of the patients with TSCI is double compared to the controls. Most deaths occur within two years postinjury. Elderly patients with more severe fall-related injury have the highest mortality risk. Circulatory diseases and pulmonary diseases, especially pneumonia, are the foremost causes of death after TSCI.
AbstractList Prospective cohort study. To study the mortality rates of TSCI patients compared to matched controls and to examine possible TSCI-related mortality risk factors and causes of death. Oulu and Tampere University Hospital, Finland. All consecutive patients with a new TSCI were included in a prospective study (n = 344, 2012-16). All patients were followed until death or the end of 2019. Patients were compared to a control group formed by randomly choosing gender, age, municipality, and calendar time-matched controls (5 controls/TSCI patient). Standardized mortality ratios (SMR) were calculated using general population mortality rates. Mortality information was extracted from the Statistics of Finland (Helsinki, Finland). TSCI patients had an increased mortality (SMR = 2.9) compared with the Finnish population. During the observation period, 26% of TSCI patients and 12% of the matched controls died. Of the TSCI patient deaths, 51% occurred within the first two years postinjury. Increased age, severity of TSCI (as per International SCI Core Data Set) and fall were related to mortality (p < 0.05). The two most common etiologies of death were: circulatory (30%), and pulmonary diseases (28%). Pneumonia was the single most frequent disease leading to death among TSCI patients. During the first years after injury, the mortality of the patients with TSCI is double compared to the controls. Most deaths occur within two years postinjury. Elderly patients with more severe fall-related injury have the highest mortality risk. Circulatory diseases and pulmonary diseases, especially pneumonia, are the foremost causes of death after TSCI.
Prospective cohort study.STUDY DESIGNProspective cohort study.To study the mortality rates of TSCI patients compared to matched controls and to examine possible TSCI-related mortality risk factors and causes of death.OBJECTIVESTo study the mortality rates of TSCI patients compared to matched controls and to examine possible TSCI-related mortality risk factors and causes of death.Oulu and Tampere University Hospital, Finland.SETTINGOulu and Tampere University Hospital, Finland.All consecutive patients with a new TSCI were included in a prospective study (n = 344, 2012-16). All patients were followed until death or the end of 2019. Patients were compared to a control group formed by randomly choosing gender, age, municipality, and calendar time-matched controls (5 controls/TSCI patient). Standardized mortality ratios (SMR) were calculated using general population mortality rates. Mortality information was extracted from the Statistics of Finland (Helsinki, Finland).METHODSAll consecutive patients with a new TSCI were included in a prospective study (n = 344, 2012-16). All patients were followed until death or the end of 2019. Patients were compared to a control group formed by randomly choosing gender, age, municipality, and calendar time-matched controls (5 controls/TSCI patient). Standardized mortality ratios (SMR) were calculated using general population mortality rates. Mortality information was extracted from the Statistics of Finland (Helsinki, Finland).TSCI patients had an increased mortality (SMR = 2.9) compared with the Finnish population. During the observation period, 26% of TSCI patients and 12% of the matched controls died. Of the TSCI patient deaths, 51% occurred within the first two years postinjury. Increased age, severity of TSCI (as per International SCI Core Data Set) and fall were related to mortality (p < 0.05). The two most common etiologies of death were: circulatory (30%), and pulmonary diseases (28%). Pneumonia was the single most frequent disease leading to death among TSCI patients.RESULTSTSCI patients had an increased mortality (SMR = 2.9) compared with the Finnish population. During the observation period, 26% of TSCI patients and 12% of the matched controls died. Of the TSCI patient deaths, 51% occurred within the first two years postinjury. Increased age, severity of TSCI (as per International SCI Core Data Set) and fall were related to mortality (p < 0.05). The two most common etiologies of death were: circulatory (30%), and pulmonary diseases (28%). Pneumonia was the single most frequent disease leading to death among TSCI patients.During the first years after injury, the mortality of the patients with TSCI is double compared to the controls. Most deaths occur within two years postinjury. Elderly patients with more severe fall-related injury have the highest mortality risk. Circulatory diseases and pulmonary diseases, especially pneumonia, are the foremost causes of death after TSCI.CONCLUSIONSDuring the first years after injury, the mortality of the patients with TSCI is double compared to the controls. Most deaths occur within two years postinjury. Elderly patients with more severe fall-related injury have the highest mortality risk. Circulatory diseases and pulmonary diseases, especially pneumonia, are the foremost causes of death after TSCI.
Author Vainionpää, Aki
Luoto, Teemu M
Koskinen, Eerika
Helminen, Mika
Johansson, Elina
Author_xml – sequence: 1
  givenname: Elina
  orcidid: 0000-0003-2159-9684
  surname: Johansson
  fullname: Johansson, Elina
  email: elina.johansson@tuni.fi
  organization: Department of Neurology, Tampere University Hospital, Wellbeing Services County of Pirkanmaa, Tampere, Finland. elina.johansson@tuni.fi
– sequence: 2
  givenname: Eerika
  surname: Koskinen
  fullname: Koskinen, Eerika
  organization: Department of Neurology, Tampere University Hospital, Wellbeing Services County of Pirkanmaa, Tampere, Finland
– sequence: 3
  givenname: Mika
  orcidid: 0000-0001-5695-2084
  surname: Helminen
  fullname: Helminen, Mika
  organization: Tays Research Services, Tampere University Hospital, Wellbeing Services County of Pirkanmaa, and Faculty of Social Sciences, Health Sciences, Tampere University, Tampere, Finland
– sequence: 4
  givenname: Aki
  surname: Vainionpää
  fullname: Vainionpää, Aki
  organization: Department of Rehabilitation, Seinäjoki Central Hospital, Seinäjoki, Finland
– sequence: 5
  givenname: Teemu M
  orcidid: 0000-0002-7329-3284
  surname: Luoto
  fullname: Luoto, Teemu M
  organization: Department of Neurosurgery, Tampere University Hospital, Wellbeing Services County of Pirkanmaa, and Tampere University, Tampere, Finland
BackLink https://www.ncbi.nlm.nih.gov/pubmed/39478103$$D View this record in MEDLINE/PubMed
BookMark eNpNj7tOAzEURC0URB7wAxTIJY3Bj7vedYkiQpCCaKBe3diOcLSPYHuL_D2LEiSqmWLOaGZOJl3feUJuBX8QXFWPCYQyinEJjAsOJTMXZCag1KzQEib__JTMU9pzzo0w1RWZKgNlNXbMyPqtjxmbkI8UO0ctDskn2u-o85i_fk2OOLSYg6XpEDpsqO2jo6HbD_E4Cl2FrhnRa3K5wyb5m7MuyOfq-WO5Zpv3l9fl04ZZkDozb3fSaHQIHJz32vlKAirNNWgrwWwL74SxBQqjhC-cdVDKQpQOR1IILhfk_tR7iP334FOu25Csb8YNvh9SrYSUGgAqGKN35-iwbb2rDzG0GI_133v5A4JiXis
ContentType Journal Article
Copyright 2024. The Author(s).
Copyright_xml – notice: 2024. The Author(s).
DBID CGR
CUY
CVF
ECM
EIF
NPM
7X8
DOI 10.1038/s41393-024-01047-9
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
DatabaseTitleList MEDLINE
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: 7X8
  name: MEDLINE - Academic
  url: https://search.proquest.com/medline
  sourceTypes: Aggregation Database
DeliveryMethod no_fulltext_linktorsrc
Discipline Medicine
EISSN 1476-5624
ExternalDocumentID 39478103
Genre Journal Article
GeographicLocations Finland
GeographicLocations_xml – name: Finland
GroupedDBID ---
-Q-
.GJ
0R~
123
2QV
2WC
36B
39C
4.4
406
53G
5RE
6PF
70F
7RV
7X7
88E
8AO
8FI
8FJ
8R4
8R5
AACDK
AANZL
AASML
AATNV
AAWTL
AAYZH
ABAKF
ABAWZ
ABBRH
ABDBE
ABDBF
ABFSG
ABJNI
ABLJU
ABRTQ
ABUWG
ABZZP
ACAOD
ACGFO
ACGFS
ACKTT
ACMJI
ACPRK
ACRQY
ACSTC
ACUHS
ACZOJ
ADBBV
ADFRT
AEFQL
AEJRE
AEMSY
AENEX
AEVLU
AEXYK
AEZWR
AFBBN
AFDZB
AFHIU
AFKRA
AFRAH
AFSHS
AGAYW
AGHAI
AGQEE
AHMBA
AHSBF
AHWEU
AIGIU
AILAN
AIXLP
AJRNO
ALFFA
ALMA_UNASSIGNED_HOLDINGS
AMYLF
ATHPR
AXYYD
AYFIA
B0M
BAWUL
BBNVY
BENPR
BHPHI
BKEYQ
BKKNO
BPHCQ
BVXVI
CAG
CCPQU
CGR
COF
CS3
CUY
CVF
DIK
DNIVK
DPUIP
DU5
DXH
E3Z
EAD
EAP
EAS
EBC
EBD
EBLON
EBS
ECM
EE.
EHN
EIF
EIOEI
EJD
EMB
EMK
EMOBN
ENB
ENC
ENX
EPL
EPT
ESX
EX3
F5P
FDQFY
FERAY
FIGPU
FIZPM
FSGXE
FYUFA
HCIFZ
HMCUK
HZ~
IWAJR
JSO
JZLTJ
KQ8
LGEZI
LOTEE
M1P
M7P
NADUK
NAPCQ
NPM
NQJWS
NXXTH
O9-
OK1
P2P
PCD
PHGZM
PHGZT
PJZUB
PPXIY
PQGLB
PQQKQ
PROAC
PSQYO
Q2X
Q~Q
RNS
RNT
RNTTT
ROL
SNX
SNYQT
SOJ
SRMVM
SV3
SWTZT
TAOOD
TBHMF
TDRGL
TR2
TUS
UKHRP
W2D
WH7
WOW
ZGI
ZXP
~8M
7X8
ID FETCH-LOGICAL-c426t-ecf296ada404dee6de824a360646c249b5ed19c5a1931e5dcd472517daecf1102
IEDL.DBID 7X8
ISICitedReferencesCount 0
ISICitedReferencesURI http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=001346011100001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN 1476-5624
IngestDate Thu Sep 04 17:40:29 EDT 2025
Sun Aug 17 02:24:28 EDT 2025
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Language English
License 2024. The Author(s).
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c426t-ecf296ada404dee6de824a360646c249b5ed19c5a1931e5dcd472517daecf1102
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ORCID 0000-0002-7329-3284
0000-0001-5695-2084
0000-0003-2159-9684
OpenAccessLink https://doi.org/10.1038/s41393-024-01047-9
PMID 39478103
PQID 3122644484
PQPubID 23479
ParticipantIDs proquest_miscellaneous_3122644484
pubmed_primary_39478103
PublicationCentury 2000
PublicationDate 2025-01-01
PublicationDateYYYYMMDD 2025-01-01
PublicationDate_xml – month: 01
  year: 2025
  text: 2025-01-01
  day: 01
PublicationDecade 2020
PublicationPlace England
PublicationPlace_xml – name: England
PublicationTitle Spinal cord
PublicationTitleAlternate Spinal Cord
PublicationYear 2025
SSID ssj0009198
Score 2.4273646
Snippet Prospective cohort study. To study the mortality rates of TSCI patients compared to matched controls and to examine possible TSCI-related mortality risk...
Prospective cohort study.STUDY DESIGNProspective cohort study.To study the mortality rates of TSCI patients compared to matched controls and to examine...
SourceID proquest
pubmed
SourceType Aggregation Database
Index Database
StartPage 24
SubjectTerms Adolescent
Adult
Aged
Aged, 80 and over
Cause of Death
Female
Finland - epidemiology
Humans
Male
Middle Aged
Pneumonia - mortality
Prospective Studies
Risk Factors
Spinal Cord Injuries - mortality
Young Adult
Title Mortality and causes of death of traumatic spinal cord injury in Finland
URI https://www.ncbi.nlm.nih.gov/pubmed/39478103
https://www.proquest.com/docview/3122644484
Volume 63
WOSCitedRecordID wos001346011100001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText
inHoldings 1
isFullTextHit
isPrint
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LSwMxEB7Uinjx_agvIngN3U2yj5xExNKDLT2o9FbSJAv1sFu7rb_fmXRLbyJ42d1LYJmZzHzzBnjInPeps4YXSk64UlHB9UQrLiaJL9B-iigMnv94zQaDfDTSwybgVjdllWudGBS1qyzFyDsyppZPdCbU4-yL09Yoyq42KzS2oSURypBUZ6PNtHAdh124scpSjnZeNU0zkcw7NSpvqlwTVINB0wp-gZjB1HQP__uTR3DQgEz2tJKKY9jy5Qns9Zs0-in0-gF0IwBnpnTMmmXta1YVzBEgpI_F3CzDMFdWz2hvFiMnlU3LT2QBvlh3WlJJ5Bm8d1_ennu8WanALZriBfe2EDo1zqhIBS75XCgj0YtRqUVPDDnkYm0Tg7gu9omzTmU01MwZPIlIQZzDTlmV_hKYzLRD8KiNsOhSusiIRGYevUUlYpf7tA33axqNUWQpD2FKXy3r8YZKbbhYEXo8W83WGEtNva-RvPrD6WvYF7SNNwREbqBV4IX1t7BrvxfTen4XZAGfg2H_BxXhvLE
linkProvider ProQuest
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Mortality+and+causes+of+death+of+traumatic+spinal+cord+injury+in+Finland&rft.jtitle=Spinal+cord&rft.au=Johansson%2C+Elina&rft.au=Koskinen%2C+Eerika&rft.au=Helminen%2C+Mika&rft.au=Vainionp%C3%A4%C3%A4%2C+Aki&rft.date=2025-01-01&rft.issn=1476-5624&rft.eissn=1476-5624&rft_id=info:doi/10.1038%2Fs41393-024-01047-9&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1476-5624&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1476-5624&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1476-5624&client=summon