SREBP transcription factors: master regulators of lipid homeostasis

Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regulate lipid homeostasis by controlling the expression of a range of enzymes required for endogenous cholesterol, fatty acid (FA), triacylglycerol and phospholipid synthesis. The three SREBP isoforms, SR...

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Vydáno v:	Biochimie Ročník 86; číslo 11; s. 839 - 848
Hlavní autoři:	Eberlé, Delphine, Hegarty, Bronwyn, Bossard, Pascale, Ferré, Pascal, Foufelle, Fabienne
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	France Elsevier Masson SAS 01.11.2004
Témata:	Animals CCAAT-Enhancer-Binding Proteins - biosynthesis CCAAT-Enhancer-Binding Proteins - genetics CCAAT-Enhancer-Binding Proteins - metabolism DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Gene Expression Regulation Homeostasis Insulin Lipid Metabolism Lipids Lipids - biosynthesis Mice Models, Biological Protein Isoforms - biosynthesis Protein Isoforms - genetics Protein Isoforms - metabolism Sterol Regulatory Element Binding Protein 1 Sterol Regulatory Element Binding Protein 2 Sterol regulatory element binding proteins (SREBPs) Transcription factors Transcription Factors - biosynthesis Transcription Factors - genetics Transcription Factors - metabolism aa ACC Transcription factors SREBP SRE Lipids bHLH-LZ Sterol regulatory element binding proteins (SREBPs) MAPK Insulin ER ADD1 TG STZ AMPK FAS SCAP FA
ISSN:	0300-9084, 1638-6183
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