Hepatic carcinoma-associated fibroblasts induce IDO-producing regulatory dendritic cells through IL-6-mediated STAT3 activation

Although carcinoma-associated fibroblasts (CAFs) in tumor microenvironments have a critical role in immune cell modulation, their effects on the generation of regulatory dendritic cells (DCs) are still unclear. In this study, we initially show that CAFs derived from hepatocellular carcinoma (HCC) tu...

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Bibliographic Details

Published in:	Oncogenesis (New York, NY) Vol. 5; no. 2; p. e198
Main Authors:	Cheng, J-t, Deng, Y-n, Yi, H-m, Wang, G-y, Fu, B-s, Chen, W-j, Liu, W, Tai, Y, Peng, Y-w, Zhang, Q
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 22.02.2016 Nature Publishing Group
Subjects:	13/21 13/31 631/67/580/1884 Apoptosis Cell Biology Human Genetics Internal Medicine Medicine Medicine & Public Health Oncology Original original-article
ISSN:	2157-9024, 2157-9024
Online Access:	Get full text
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