ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer

Review evaluates the possible physiological roles of MDR‐related ABC transporters on immune effector cells based on reports on their expression patterns and immune‐related substrates. ABC transporters were identified originally for their contribution to clinical MDR as a result of their capacity to...

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Bibliographic Details
Published in:	Journal of leukocyte biology Vol. 86; no. 5; pp. 1075 - 1087
Main Authors:	Ven, Rieneke, Oerlemans, Ruud, Heijden, Joost W., Scheffer, George L., Gruijl, Tanja D., Jansen, Gerrit, Scheper, Rik J.
Format:	Journal Article
Language:	English
Published:	United States Society for Leukocyte Biology 01.11.2009
Subjects:	Antineoplastic Agents - therapeutic use ATP-Binding Cassette Transporters - immunology ATP-Binding Cassette Transporters - physiology autoimmune diseases Autoimmune Diseases - immunology Autoimmune Diseases - therapy Autoimmunity - drug effects Autoimmunity - genetics drug resistance Drug Resistance, Neoplasm - drug effects Drug Resistance, Neoplasm - genetics Drug Resistance, Neoplasm - immunology Humans immune system Immunity - drug effects Immunity - genetics immunotherapy Immunotherapy - methods Neoplasms - drug therapy Neoplasms - genetics Neoplasms - immunology
ISSN:	0741-5400, 1938-3673, 1938-3673
Online Access:	Get full text
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