Altered plasma adipokine levels and in vitro adipocyte differentiation in pediatric type 1 diabetes

Type 1 diabetes (T1D) is considered a proinflammatory condition. Adipose tissue involvement seems evident because adiponectin levels correlate with disease remission and administration of leptin suppresses the low-grade systemic inflammation in mice with T1D. Whether adipose tissue involvement in T1...

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Vydáno v:	The journal of clinical endocrinology and metabolism Ročník 97; číslo 2; s. 463
Hlavní autoři:	Verrijn Stuart, A A, Schipper, H S, Tasdelen, I, Egan, D A, Prakken, B J, Kalkhoven, E, de Jager, W
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.02.2012
Témata:	Adipocytes - pathology Adipocytes - physiology Adipokines - blood Adolescent Cell Differentiation - drug effects Cells, Cultured Child Cohort Studies Culture Media, Conditioned - pharmacology Cytokines - blood Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - pathology Diabetes Mellitus, Type 1 - physiopathology Fatty Acids, Nonesterified - blood Fatty Acids, Nonesterified - physiology Female Humans Hyperglycemia - blood Hyperglycemia - complications Hyperglycemia - pathology Hyperglycemia - physiopathology Male Primary Cell Culture
ISSN:	1945-7197, 1945-7197
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