Reframing the association and significance of co-morbidities in heart failure

Several co‐existing diseases and/or conditions (co‐morbidities) are present in patients with heart failure (HF), with diverse clinical relevance. Multiple mechanisms may underlie the co‐existence of HF and co‐morbidities, including direct causation, associated risk factors, heterogeneity, and indepe...

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Bibliographic Details
Published in:European journal of heart failure Vol. 18; no. 7; pp. 744 - 758
Main Authors: Triposkiadis, Filippos, Giamouzis, Gregory, Parissis, John, Starling, Randall C., Boudoulas, Harisios, Skoularigis, John, Butler, Javed, Filippatos, Gerasimos
Format: Journal Article
Language:English
Published: Oxford, UK John Wiley & Sons, Ltd 01.07.2016
Subjects:
Anaemia
Anemia - epidemiology
Atrial Fibrillation - epidemiology
Atrial fibrillation
Causality
Comorbidity
Coronary artery disease
Coronary Artery Disease - epidemiology
Depression
Depressive Disorder - epidemiology
Diabetes
Diabetes Mellitus - epidemiology
Heart failure
Heart Failure - epidemiology
Heart Failure - physiopathology
Humans
Hypertension
Hypertension - epidemiology
Incidence
Kidney disease
Myocardial infarction
Obesity
Obesity - epidemiology
Obstructive pulmonary disease
Prevalence
Pulmonary Disease, Chronic Obstructive - epidemiology
Renal failure
Renal Insufficiency, Chronic - epidemiology
Risk Factors
Sleep Apnea Syndromes - epidemiology
Sleep-disordered breathing
Stroke Volume - physiology
Heart failure
Hypertension
Kidney disease
Myocardial infarction
Obesity
Anaemia
Atrial fibrillation
Depression
Coronary artery disease
Sleep-disordered breathing
Renal failure
Diabetes
Obstructive pulmonary disease
ISSN:1388-9842, 1879-0844
Online Access:Get full text
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Summary:Several co‐existing diseases and/or conditions (co‐morbidities) are present in patients with heart failure (HF), with diverse clinical relevance. Multiple mechanisms may underlie the co‐existence of HF and co‐morbidities, including direct causation, associated risk factors, heterogeneity, and independence. The complex inter‐relationship of co‐morbidities and their impact on the cardiovascular system contribute to the features of HF, both with reduced (HFrEF) and preserved ejection fraction (HFpEF). The purpose of this work is to provide an overview of the contribution of major cardiac and non‐cardiac co‐morbidities to HF development and outcomes, in the context of both HFpEF and HFrEF. Accordingly, epidemiological evidence linking co‐morbidities to HF and the effect of prevalent and incident co‐morbidities on HF outcome will be reviewed.
Bibliography:istex:BDB96455EBE99A567046FE467C721CB326047213
ark:/67375/WNG-JNMD0150-Q
ArticleID:EJHF600
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:1388-9842
1879-0844
DOI:10.1002/ejhf.600