Reframing the association and significance of co-morbidities in heart failure

Several co‐existing diseases and/or conditions (co‐morbidities) are present in patients with heart failure (HF), with diverse clinical relevance. Multiple mechanisms may underlie the co‐existence of HF and co‐morbidities, including direct causation, associated risk factors, heterogeneity, and indepe...

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Vydané v:	European journal of heart failure Ročník 18; číslo 7; s. 744 - 758
Hlavní autori:	Triposkiadis, Filippos, Giamouzis, Gregory, Parissis, John, Starling, Randall C., Boudoulas, Harisios, Skoularigis, John, Butler, Javed, Filippatos, Gerasimos
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Oxford, UK John Wiley & Sons, Ltd 01.07.2016
Predmet:	Anaemia Anemia - epidemiology Atrial Fibrillation - epidemiology Atrial fibrillation Causality Comorbidity Coronary artery disease Coronary Artery Disease - epidemiology Depression Depressive Disorder - epidemiology Diabetes Diabetes Mellitus - epidemiology Heart failure Heart Failure - epidemiology Heart Failure - physiopathology Humans Hypertension Hypertension - epidemiology Incidence Kidney disease Myocardial infarction Obesity Obesity - epidemiology Obstructive pulmonary disease Prevalence Pulmonary Disease, Chronic Obstructive - epidemiology Renal failure Renal Insufficiency, Chronic - epidemiology Risk Factors Sleep Apnea Syndromes - epidemiology Sleep-disordered breathing Stroke Volume - physiology Heart failure Hypertension Kidney disease Myocardial infarction Obesity Anaemia Atrial fibrillation Depression Coronary artery disease Sleep-disordered breathing Renal failure Diabetes Obstructive pulmonary disease
ISSN:	1388-9842, 1879-0844
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Popis
Shrnutí:	Several co‐existing diseases and/or conditions (co‐morbidities) are present in patients with heart failure (HF), with diverse clinical relevance. Multiple mechanisms may underlie the co‐existence of HF and co‐morbidities, including direct causation, associated risk factors, heterogeneity, and independence. The complex inter‐relationship of co‐morbidities and their impact on the cardiovascular system contribute to the features of HF, both with reduced (HFrEF) and preserved ejection fraction (HFpEF). The purpose of this work is to provide an overview of the contribution of major cardiac and non‐cardiac co‐morbidities to HF development and outcomes, in the context of both HFpEF and HFrEF. Accordingly, epidemiological evidence linking co‐morbidities to HF and the effect of prevalent and incident co‐morbidities on HF outcome will be reviewed.
Bibliografia:	istex:BDB96455EBE99A567046FE467C721CB326047213 ark:/67375/WNG-JNMD0150-Q ArticleID:EJHF600 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	1388-9842 1879-0844
DOI:	10.1002/ejhf.600