Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status

Intravital imaging guides a personalized medicine approach to target mechanoreciprocity in pancreatic cancer. Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic, chemoresistant malignancy and is characterized by a dense, desmoplastic stroma that modulates PDAC progression. Here, we visua...

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Vydáno v:	Science advances Ročník 7; číslo 40; s. eabh0363
Hlavní autoři:	Murphy, Kendelle J., Reed, Daniel A., Vennin, Claire, Conway, James R. W., Nobis, Max, Yin, Julia X., Chambers, Cecilia R., Pereira, Brooke A., Lee, Victoria, Filipe, Elysse C., Trpceski, Michael, Ritchie, Shona, Lucas, Morghan C., Warren, Sean C., Skhinas, Joanna N., Magenau, Astrid, Metcalf, Xanthe L., Stoehr, Janett, Major, Gretel, Parkin, Ashleigh, Bidanel, Romain, Lyons, Ruth J., Zaratzian, Anaiis, Tayao, Michael, Da Silva, Andrew, Abdulkhalek, Lea, Gill, Anthony J., Johns, Amber L., Biankin, Andrew V., Samra, Jaswinder, Grimmond, Sean M., Chou, Angela, Goetz, Jacky G., Samuel, Michael S., Lyons, J. Guy, Burgess, Andrew, Caldon, C. Elizabeth, Horvath, Lisa G., Daly, Roger J., Gadegaard, Nikolaj, Wang, Yingxiao, Sansom, Owen J., Morton, Jennifer P., Cox, Thomas R., Pajic, Marina, Herrmann, David, Timpson, Paul
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States American Association for the Advancement of Science (AAAS) 01.10.2021 American Association for the Advancement of Science
Témata:	Biomedicine and Life Sciences Cancer Cell Biology Computer Science Medical Imaging SciAdv r-articles
ISSN:	2375-2548, 2375-2548
On-line přístup:	Získat plný text
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