Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants

Nirsevimab, a monoclonal antibody with an extended half-life, is designed to protect infants from respiratory syncytial virus disease after a single intramuscular dose. This placebo-controlled trial involving 1447 preterm infants at 164 sites in 23 countries assessed the effectiveness of nirsevimab...

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Vydáno v:	The New England journal of medicine Ročník 383; číslo 5; s. 415 - 425
Hlavní autoři:	Griffin, M. Pamela, Yuan, Yuan, Takas, Therese, Domachowske, Joseph B, Madhi, Shabir A, Manzoni, Paolo, Simões, Eric A.F, Esser, Mark T, Khan, Anis A, Dubovsky, Filip, Villafana, Tonya, DeVincenzo, John P
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Massachusetts Medical Society 30.07.2020
Témata:	Antibodies Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal - adverse effects Antibodies, Monoclonal, Humanized - administration & dosage Antibodies, Monoclonal, Humanized - adverse effects Antiviral Agents - administration & dosage Antiviral Agents - adverse effects FDA approval Female Gestation Gestational age Health care Hospitalization Hospitalization - statistics & numerical data Humans Hypersensitivity Incidence Infant Infant, Newborn Infant, Premature Infants Infections Injection Injections, Intramuscular Kaplan-Meier Estimate Laboratories Life Sciences Male Monoclonal antibodies Newborn babies Pharmacokinetics Poisson Distribution Premature babies Prophylaxis Respiratory diseases Respiratory syncytial virus Respiratory Syncytial Virus Infections - epidemiology Respiratory Syncytial Virus Infections - prevention & control Respiratory Syncytial Virus, Human Respiratory tract diseases Respiratory Tract Infections - epidemiology Respiratory Tract Infections - prevention & control Respiratory Tract Infections - virology Vaccines Viral Fusion Proteins - antagonists & inhibitors Vitamin E Writers United States > US
ISSN:	0028-4793, 1533-4406, 1533-4406
On-line přístup:	Získat plný text
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