Allantoin Inhibits Compound 48/80-Induced Pseudoallergic Reactions In Vitro and In Vivo

Pseudoallergic reactions are hypersensitivity reactions mediated by an IgE-independent mechanism. Since allantoin (AT)-mediated pseudoallergy has not been studied, in this study, our objective is to investigate the anti-pseudoallergy effect of AT and its underlying mechanism. In vitro, β-hexosaminid...

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Bibliographic Details
Published in:	Molecules (Basel, Switzerland) Vol. 27; no. 11; p. 3473
Main Authors:	Zhang, Ping, Wang, Yanjie, Zhang, Jingyu, Hong, Tie
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 27.05.2022 MDPI
Subjects:	allantoin Anaphylaxis Body temperature Cytokines Cytoskeleton degranulation Histamine Inflammation Kinases mast cells Phosphorylation Proteins pseudoallergy Skin pseudoallergy degranulation mast cells allantoin
ISSN:	1420-3049, 1420-3049
Online Access:	Get full text
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