Cervical cancer: A global health crisis

Cervical cancer is the fourth most common malignancy diagnosed in women worldwide. Nearly all cases of cervical cancer result from infection with the human papillomavirus, and the prevention of cervical cancer includes screening and vaccination. Primary treatment options for patients with cervical c...

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Veröffentlicht in:Cancer Jg. 123; H. 13; S. 2404 - 2412
Hauptverfasser: Small, William, Bacon, Monica A., Bajaj, Amishi, Chuang, Linus T., Fisher, Brandon J., Harkenrider, Matthew M., Jhingran, Anuja, Kitchener, Henry C., Mileshkin, Linda R., Viswanathan, Akila N., Gaffney, David K.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Wiley Subscription Services, Inc 01.07.2017
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ISSN:0008-543X, 1097-0142, 1097-0142
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Abstract Cervical cancer is the fourth most common malignancy diagnosed in women worldwide. Nearly all cases of cervical cancer result from infection with the human papillomavirus, and the prevention of cervical cancer includes screening and vaccination. Primary treatment options for patients with cervical cancer may include surgery or a concurrent chemoradiotherapy regimen consisting of cisplatin‐based chemotherapy with external beam radiotherapy and brachytherapy. Cervical cancer causes more than one quarter of a million deaths per year as a result of grossly deficient treatments in many developing countries. This warrants a concerted global effort to counter the shocking loss of life and suffering that largely goes unreported. This article provides a review of the biology, prevention, and treatment of cervical cancer, and discusses the global cervical cancer crisis and efforts to improve the prevention and treatment of the disease in underdeveloped countries. Cancer 2017;123:2404–12. © 2017 American Cancer Society. Cervical cancer is a leading cause of death worldwide. In this article, the authors discuss the biology, prevention, and treatment of this disease, in addition to activist efforts aimed at improving treatment and access to care.
AbstractList Cervical cancer is the fourth most common malignancy diagnosed in women worldwide. Nearly all cases of cervical cancer result from infection with the human papillomavirus, and the prevention of cervical cancer includes screening and vaccination. Primary treatment options for patients with cervical cancer may include surgery or a concurrent chemoradiotherapy regimen consisting of cisplatin-based chemotherapy with external beam radiotherapy and brachytherapy. Cervical cancer causes more than one quarter of a million deaths per year as a result of grossly deficient treatments in many developing countries. This warrants a concerted global effort to counter the shocking loss of life and suffering that largely goes unreported. This article provides a review of the biology, prevention, and treatment of cervical cancer, and discusses the global cervical cancer crisis and efforts to improve the prevention and treatment of the disease in underdeveloped countries. Cancer 2017;123:2404-12. © 2017 American Cancer Society.
Cervical cancer is the fourth most common malignancy diagnosed in women worldwide. Nearly all cases of cervical cancer result from infection with the human papillomavirus, and the prevention of cervical cancer includes screening and vaccination. Primary treatment options for patients with cervical cancer may include surgery or a concurrent chemoradiotherapy regimen consisting of cisplatin-based chemotherapy with external beam radiotherapy and brachytherapy. Cervical cancer causes more than one quarter of a million deaths per year as a result of grossly deficient treatments in many developing countries. This warrants a concerted global effort to counter the shocking loss of life and suffering that largely goes unreported. This article provides a review of the biology, prevention, and treatment of cervical cancer, and discusses the global cervical cancer crisis and efforts to improve the prevention and treatment of the disease in underdeveloped countries. Cancer 2017;123:2404-12. © 2017 American Cancer Society. Cervical cancer is a leading cause of death worldwide. In this article, the authors discuss the biology, prevention, and treatment of this disease, in addition to activist efforts aimed at improving treatment and access to care.
Cervical cancer is the fourth most common malignancy diagnosed in women worldwide. Nearly all cases of cervical cancer result from infection with the human papillomavirus, and the prevention of cervical cancer includes screening and vaccination. Primary treatment options for patients with cervical cancer may include surgery or a concurrent chemoradiotherapy regimen consisting of cisplatin‐based chemotherapy with external beam radiotherapy and brachytherapy. Cervical cancer causes more than one quarter of a million deaths per year as a result of grossly deficient treatments in many developing countries. This warrants a concerted global effort to counter the shocking loss of life and suffering that largely goes unreported. This article provides a review of the biology, prevention, and treatment of cervical cancer, and discusses the global cervical cancer crisis and efforts to improve the prevention and treatment of the disease in underdeveloped countries. Cancer 2017;123:2404–12. © 2017 American Cancer Society . Cervical cancer is a leading cause of death worldwide. In this article, the authors discuss the biology, prevention, and treatment of this disease, in addition to activist efforts aimed at improving treatment and access to care.
Cervical cancer is the fourth most common malignancy diagnosed in women worldwide. Nearly all cases of cervical cancer result from infection with the human papillomavirus, and the prevention of cervical cancer includes screening and vaccination. Primary treatment options for patients with cervical cancer may include surgery or a concurrent chemoradiotherapy regimen consisting of cisplatin-based chemotherapy with external beam radiotherapy and brachytherapy. Cervical cancer causes more than one quarter of a million deaths per year as a result of grossly deficient treatments in many developing countries. This warrants a concerted global effort to counter the shocking loss of life and suffering that largely goes unreported. This article provides a review of the biology, prevention, and treatment of cervical cancer, and discusses the global cervical cancer crisis and efforts to improve the prevention and treatment of the disease in underdeveloped countries. Cancer 2017;123:2404-12. © 2017 American Cancer Society.Cervical cancer is the fourth most common malignancy diagnosed in women worldwide. Nearly all cases of cervical cancer result from infection with the human papillomavirus, and the prevention of cervical cancer includes screening and vaccination. Primary treatment options for patients with cervical cancer may include surgery or a concurrent chemoradiotherapy regimen consisting of cisplatin-based chemotherapy with external beam radiotherapy and brachytherapy. Cervical cancer causes more than one quarter of a million deaths per year as a result of grossly deficient treatments in many developing countries. This warrants a concerted global effort to counter the shocking loss of life and suffering that largely goes unreported. This article provides a review of the biology, prevention, and treatment of cervical cancer, and discusses the global cervical cancer crisis and efforts to improve the prevention and treatment of the disease in underdeveloped countries. Cancer 2017;123:2404-12. © 2017 American Cancer Society.
Author Chuang, Linus T.
Kitchener, Henry C.
Harkenrider, Matthew M.
Bajaj, Amishi
Jhingran, Anuja
Viswanathan, Akila N.
Small, William
Gaffney, David K.
Fisher, Brandon J.
Mileshkin, Linda R.
Bacon, Monica A.
Author_xml – sequence: 1
  givenname: William
  orcidid: 0000-0002-1623-9863
  surname: Small
  fullname: Small, William
  email: wmsmall@lumc.edu
  organization: Stritch School of Medicine, Loyola University
– sequence: 2
  givenname: Monica A.
  surname: Bacon
  fullname: Bacon, Monica A.
  organization: Gynecological Cancer InterGroup
– sequence: 3
  givenname: Amishi
  surname: Bajaj
  fullname: Bajaj, Amishi
  organization: Stritch School of Medicine, Loyola University
– sequence: 4
  givenname: Linus T.
  surname: Chuang
  fullname: Chuang, Linus T.
  organization: Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai
– sequence: 5
  givenname: Brandon J.
  surname: Fisher
  fullname: Fisher, Brandon J.
  organization: Gamma West Cancer Services
– sequence: 6
  givenname: Matthew M.
  surname: Harkenrider
  fullname: Harkenrider, Matthew M.
  organization: Stritch School of Medicine, Loyola University
– sequence: 7
  givenname: Anuja
  surname: Jhingran
  fullname: Jhingran, Anuja
  organization: The University of Texas MD Anderson Cancer Center
– sequence: 8
  givenname: Henry C.
  surname: Kitchener
  fullname: Kitchener, Henry C.
  organization: University of Manchester
– sequence: 9
  givenname: Linda R.
  surname: Mileshkin
  fullname: Mileshkin, Linda R.
  organization: Peter MacCallum Cancer Centre
– sequence: 10
  givenname: Akila N.
  surname: Viswanathan
  fullname: Viswanathan, Akila N.
  organization: Johns Hopkins University School of Medicine
– sequence: 11
  givenname: David K.
  surname: Gaffney
  fullname: Gaffney, David K.
  organization: Huntsman Cancer Institute, University of Utah
BackLink https://www.ncbi.nlm.nih.gov/pubmed/28464289$$D View this record in MEDLINE/PubMed
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Issue 13
Keywords human papillomavirus (HPV)
developing world
Cervix Cancer Research Network (CCRN)
Gynecological Cancer InterGroup (GCIG)
brachytherapy
cervical cancer
chemotherapy
activism
vaccination
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2017 American Cancer Society.
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Snippet Cervical cancer is the fourth most common malignancy diagnosed in women worldwide. Nearly all cases of cervical cancer result from infection with the human...
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SubjectTerms activism
Adenocarcinoma, Clear Cell - pathology
Adenocarcinoma, Clear Cell - therapy
Antineoplastic Agents - therapeutic use
Biology
Brachytherapy
Cancer
Cancer therapies
Carcinoma, Adenosquamous - pathology
Carcinoma, Adenosquamous - therapy
Carcinoma, Neuroendocrine - pathology
Carcinoma, Neuroendocrine - therapy
Carcinoma, Small Cell - pathology
Carcinoma, Small Cell - therapy
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - prevention & control
Carcinoma, Squamous Cell - therapy
Carcinoma, Squamous Cell - virology
Cervical cancer
Cervix
Cervix Cancer Research Network (CCRN)
Chemoradiotherapy
Chemoradiotherapy, Adjuvant
Chemotherapy
Cisplatin
Cisplatin - therapeutic use
Developing countries
developing world
Early Detection of Cancer
Early Medical Intervention
Female
Fertility Preservation
Global Health
Gynecological Cancer InterGroup (GCIG)
Human papillomavirus
human papillomavirus (HPV)
Humans
Hysterectomy
Infections
LDCs
Malignancy
Neoplasms, Cystic, Mucinous, and Serous - pathology
Neoplasms, Cystic, Mucinous, and Serous - therapy
Oncology
Papillomavirus Infections - prevention & control
Papillomavirus Vaccines - therapeutic use
Prevention
Radiation therapy
Radiotherapy, Adjuvant
Surgery
Uterine Cervical Neoplasms - pathology
Uterine Cervical Neoplasms - prevention & control
Uterine Cervical Neoplasms - therapy
Uterine Cervical Neoplasms - virology
Vaccination
Title Cervical cancer: A global health crisis
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fcncr.30667
https://www.ncbi.nlm.nih.gov/pubmed/28464289
https://www.proquest.com/docview/1920462280
https://www.proquest.com/docview/1894918443
Volume 123
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