Estrogen receptor signaling in prostate cancer: Implications for carcinogenesis and tumor progression

Background The androgen receptor (AR) is the classical target for prostate cancer prevention and treatment, but more recently estrogens and their receptors have also been implicated in prostate cancer development and tumor progression. Methods Recent experimental and clinical data were reviewed to e...

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Vydané v:	The Prostate Ročník 78; číslo 1; s. 2 - 10
Hlavný autor:	Bonkhoff, Helmut
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Wiley Subscription Services, Inc 01.01.2018
Predmet:	17β-Estradiol Androgen receptors Animal models Basal cells Carcinogenesis Carcinogenesis - metabolism Carcinogenesis - pathology Castration Cell Transformation, Neoplastic - metabolism Cell Transformation, Neoplastic - pathology CRPC Disease Progression Epithelium ER alpha ER beta Estrogen receptors Estrogens HGPIN Humans Male Metastases Orphan receptors Presenilin 2 Progesterone Progestin Prostate cancer Prostatic intraepithelial neoplasia Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Receptors, Estrogen - metabolism Reviews Signal Transduction - physiology Stromal cells Therapeutic applications Tumor suppressor genes Tumors CRPC HGPIN ER alpha ER beta
ISSN:	0270-4137, 1097-0045, 1097-0045
On-line prístup:	Získať plný text
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