Polynucleotide-based treatments for various facial scars including combat injuries

This study examines the therapeutic efficacy of polynucleotide-based therapies, specifically REJURAN , for managing scars and burns. Scars and burns present significant challenges in dermatology, often affecting patients' quality of life. Traditional treatments can be limited in effectiveness,...

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Bibliographic Details
Published in:The Journal of dermatological treatment Vol. 35; no. 1; p. 2426626
Main Authors: Kim, Michael James, Wan, Jovian, Oksana, Lopatkina, Yuliia, Lavrik, Chugay, Olena, Platonova, Olena, Sydorchuk, Olena, Yi, Kyu-Ho
Format: Journal Article
Language:English
Published: England Taylor & Francis Group 01.12.2024
Subjects:
Adolescent
Adult
burn
Burns - complications
Burns - therapy
Cicatrix - drug therapy
Cicatrix - etiology
Cicatrix - pathology
Cicatrix - therapy
Combined Modality Therapy
Facial Injuries
Female
Humans
Male
Middle Aged
Platelet-Rich Plasma
Polynucleotide
Polynucleotides
regeneration
scar
Treatment Outcome
wound
Young Adult
burn
wound
Polynucleotide
scar
regeneration
ISSN:0954-6634, 1471-1753, 1471-1753
Online Access:Get full text
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Summary:This study examines the therapeutic efficacy of polynucleotide-based therapies, specifically REJURAN , for managing scars and burns. Scars and burns present significant challenges in dermatology, often affecting patients' quality of life. Traditional treatments can be limited in effectiveness, prompting the exploration of innovative approaches like polynucleotide therapy, which utilizes salmon DNA to stimulate tissue repair, modulate inflammation, and enhance collagen production. A series of case studies was conducted, including diverse patient profiles with various types of scars and burns. The study evaluated the impact of REJURAN on scar appearance, texture, and overall skin quality. Some cases also explored the combination of polynucleotide therapy with other treatments such as Platelet-Rich Plasma (PRP) and botulinum toxin. Notable improvements were observed across cases, including reduced scar visibility and enhanced skin texture. The therapy proved effective in treating post-traumatic, post-operative, and burn-related scars, demonstrating its versatility and potential benefits. Combination therapies showed promising results, though further research is needed. Polynucleotide-based therapy with REJURAN shows promise in scar and burn management, offering a novel approach that leverages the body's regenerative processes. Further studies are recommended to confirm these findings and refine treatment protocols.
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ISSN:0954-6634
1471-1753
1471-1753
DOI:10.1080/09546634.2024.2426626