A real-world pharmacovigilance assessment and literature review of lymphoma development in lipodystrophy

Metreleptin is a form of leptin replacement therapy used with diet and lifestyle modifications to treat the metabolic complications of leptin deficiency in lipodystrophy, a rare disease characterized by adipose tissue deficiency. Previously, identification of T-cell lymphomas in three metreleptin-tr...

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Bibliographic Details
Published in:	Frontiers in endocrinology (Lausanne) Vol. 16; p. 1582715
Main Authors:	Brown, Rebecca J., Araujo-Vilar, David, Walkovich, Kelly J., Barbarosie, Alexandru, Magee, David A., Akinci, Baris, Oral, Elif A.
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 21.05.2025
Subjects:	acquired generalized lipodystrophy Adult autoimmunity B cell lymphoma Endocrinology Female Humans Leptin - adverse effects Leptin - analogs & derivatives Leptin - therapeutic use lipodystrophy Lipodystrophy - complications Lipodystrophy - drug therapy lymphoma Lymphoma - chemically induced Lymphoma - epidemiology Male Middle Aged Pharmacovigilance T-cell lymphoma acquired generalized lipodystrophy autoimmunity B cell lymphoma lymphoma metreleptin pharmacovigilance T-cell lymphoma lipodystrophy
ISSN:	1664-2392, 1664-2392
Online Access:	Get full text
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