Short-range human cortico-cortical white matter fibers have thinner axons and are less myelinated compared to long-range fibers despite a similar g-ratio

The size and complexity of the human brain require optimally sized and myelinated fibers. White matter fibers facilitate fast communication between distant areas, but also connect adjacent cortical regions via short association fibers. The difference in length and packing density of long and short a...

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Bibliographic Details
Published in:	PLoS biology Vol. 23; no. 8; p. e3002906
Main Authors:	Ruthig, Philip, von der Planitz, David Edler, Morozova, Maria, Reimann, Katja, Jäger, Carsten, Reinert, Tilo, Mohammadi, Siawoosh, Weiskopf, Nikolaus, Kirilina, Evgeniya, Morawski, Markus
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.08.2025 Public Library of Science (PLoS)
Subjects:	Adult Axons Axons - physiology Axons - ultrastructure Brain Brain architecture Cerebral Cortex - ultrastructure Corpus callosum Corpus Callosum - ultrastructure Deep learning Diameters Female Fibers G ratio Humans Hypotheses Long fibers Male Microscopic analysis Microscopy, Electron, Transmission Middle Aged Myelin Myelin Sheath - metabolism Myelin Sheath - physiology Myelin Sheath - ultrastructure Myelination Nerve Fibers, Myelinated - physiology Nerve Fibers, Myelinated - ultrastructure Optimization Packing density Semantics Short fibers Substantia alba Thickness Two dimensional analysis White Matter - physiology White Matter - ultrastructure
ISSN:	1545-7885, 1544-9173, 1545-7885
Online Access:	Get full text
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