Mechanism of Enhanced Dermal Permeation of 4-Cyanophenol and Methyl Paraben from Saturated Aqueous Solutions Containing Both Solutes

Dermal permeation through human epidermis and uptake into isolated human stratum corneum (SC) that was and was not delipidized were measured for 2 model compounds, 4-cyanophenol (CP) and methyl paraben (MP), from saturated aqueous solutions containing 1 or both compounds. Because the solutions were...

Full description

Saved in:

Bibliographic Details
Published in:	Skin pharmacology and physiology Vol. 23; no. 3; pp. 152 - 163
Main Authors:	Romonchuk, W.J., Bunge, A.L.
Format:	Journal Article
Language:	English
Published:	Basel, Switzerland S. Karger AG 01.01.2010
Subjects:	Aged Epidermis - metabolism Excipients - chemistry Excipients - pharmacokinetics Female Humans In Vitro Techniques Lipid Metabolism Male Original Paper Parabens - chemistry Parabens - pharmacokinetics Permeability Phenols - chemistry Phenols - pharmacokinetics Skin Absorption Solubility Thermodynamics 4-Cyanophenol Enhancer Stratum corneum uptake Thermodynamic activity Methyl paraben Saturated aqueous solution Dermal permeation
ISSN:	1660-5527, 1660-5535, 1660-5535
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!