Principles of and advances in percutaneous ablation

Image-guided tumor ablation with both thermal and nonthermal sources has received substantial attention for the treatment of many focal malignancies. Increasing interest has been accompanied by continual advances in energy delivery, application technique, and therapeutic combinations with the intent...

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Bibliographic Details
Published in:Radiology Vol. 258; no. 2; p. 351
Main Authors: Ahmed, Muneeb, Brace, Christopher L, Lee, Jr, Fred T, Goldberg, S Nahum
Format: Journal Article
Language:English
Published: United States 01.02.2011
Subjects:
Animals
Catheter Ablation - instrumentation
Catheter Ablation - methods
Chemoembolization, Therapeutic - instrumentation
Chemoembolization, Therapeutic - methods
Combined Modality Therapy
Humans
Minimally Invasive Surgical Procedures - instrumentation
Minimally Invasive Surgical Procedures - methods
Neoplasms - drug therapy
Neoplasms - surgery
Radiography, Interventional
ISSN:1527-1315, 1527-1315
Online Access:Get more information
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Summary:Image-guided tumor ablation with both thermal and nonthermal sources has received substantial attention for the treatment of many focal malignancies. Increasing interest has been accompanied by continual advances in energy delivery, application technique, and therapeutic combinations with the intent to improve the efficacy and/or specificity of ablative therapies. This review outlines clinical percutaneous tumor ablation technology, detailing the science, devices, techniques, technical obstacles, current trends, and future goals in percutaneous tumor ablation. Methods such as chemical ablation, cryoablation, high-temperature ablation (radiofrequency, microwave, laser, and ultrasound), and irreversible electroporation will be discussed. Advances in technique will also be covered, including combination therapies, tissue property modulation, and the role of computer modeling for treatment optimization.
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ISSN:1527-1315
1527-1315
DOI:10.1148/radiol.10081634