Information capacity of genetic regulatory elements

Changes in a cell's external or internal conditions are usually reflected in the concentrations of the relevant transcription factors. These proteins in turn modulate the expression levels of the genes under their control and sometimes need to perform nontrivial computations that integrate seve...

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Bibliographic Details

Published in:	Physical review. E, Statistical, nonlinear, and soft matter physics Vol. 78; no. 1; p. 011910
Main Authors:	Tkačik, Gašper, Callan, Curtis G., Bialek, William
Format:	Journal Article
Language:	English
Published:	United States 01.07.2008
Subjects:	Algorithms Animals Biophysics - methods Computational Biology Diffusion Humans Models, Biological Models, Genetic Models, Statistical Regulatory Sequences, Nucleic Acid Transcription Factors - genetics Transcription, Genetic
ISSN:	1539-3755, 1550-2376
Online Access:	Get full text
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