ECT-induced primary open-angle glaucoma in a patient with unstable thyroid function: a case report

Schizophrenia is a prevalent and severe psychiatric disorder for which electroconvulsive therapy (ECT) is frequently utilized as a treatment modality. Although ECT can transiently elevate intraocular pressure, the incidence of ECT-related adverse ophthalmic events in patients with coexisting hyperth...

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Published in:Frontiers in psychiatry Vol. 16; p. 1497205
Main Authors: Fu, Cuiyuan, Yang, Xiuzhen, Li, Kun
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 05.03.2025
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ISSN:1664-0640, 1664-0640
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Summary:Schizophrenia is a prevalent and severe psychiatric disorder for which electroconvulsive therapy (ECT) is frequently utilized as a treatment modality. Although ECT can transiently elevate intraocular pressure, the incidence of ECT-related adverse ophthalmic events in patients with coexisting hyperthyroidism is not well documented. In this report, we describe an elderly woman with schizophrenia and hyperthyroidism. Before undergoing ECT, she had no previous history of glaucoma, and her thyroid function was in an unstable state. After three sessions of ECT, the patient exhibited conjunctival congestion and was subsequently diagnosed with primary open-angle glaucoma, which was not treated. Her intraocular pressure normalized prior to and following the fourth ECT session, and she experienced no further ocular discomfort during subsequent treatments (fifth through eighth sessions). Although ECT has been used in patients with coexisting psychiatric and thyroid dysfunction, there is a lack of reports addressing the risk of inducing or exacerbating glaucoma in the context of unstable thyroid function. This case emphasizes the necessity of monitoring intraocular pressure in patients with unstable thyroid function during ECT, to mitigate the risk of ocular complications.
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Edited by: Gabriele Nibbio, University of Brescia, Italy
Octavian Vasiliu, Dr. Carol Davila University Emergency Military Central Hospital, BRomania
Reviewed by: Ana Mafalda Lavrador De Jesus Carvalheiro, Serviço de Psiquiatria e Saúde Mental da Unidade Local de Saúde da Região de Leiria, Portugal
ISSN:1664-0640
1664-0640
DOI:10.3389/fpsyt.2025.1497205