Medullary Thyroid Carcinoma: Survival Analysis and Evaluation of Mutation-Specific Immunohistochemistry in Detection of Sporadic Disease

Introduction Medullary thyroid cancer (MTC) is a rare tumour of neuroendocrine origin with a more aggressive profile than differentiated thyroid cancer. Familial cases of MTC are associated with RET mutations whilst RAS mutations appear to be a frequent finding in RET negative tumours. The aims of t...

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Bibliographic Details
Published in:	World journal of surgery Vol. 42; no. 5; pp. 1432 - 1439
Main Authors:	Jayakody, S., Reagh, J., Bullock, M., Aniss, A., Clifton-Bligh, R., Learoyd, D., Robinson, B., Delbridge, L., Sidhu, S., Gill, A. J., Sywak, M.
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01.05.2018 John Wiley & Sons, Inc
Subjects:	Abdominal Surgery Age Calcitonin Cancer Cardiac Surgery Females General Surgery Genetic screening Identification methods Immunohistochemistry Males Medicine Medicine & Public Health Metastases Multiple endocrine neoplasia Multivariate analysis Mutation Neuroendocrine tumors Original Scientific Report Patients Surgery Survival Survival analysis Thoracic Surgery Thyroid Thyroid cancer Thyroid carcinoma Tumors Vascular Surgery
ISSN:	0364-2313, 1432-2323, 1432-2323
Online Access:	Get full text
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