Localized Retinal Nerve Fiber Layer Defects in Red-free Photographs Versus En Face Structural Optical Coherence Tomography Images
The purpose of this article is to compare the locations of localized retinal nerve fiber layer (RNFL) defects in red-free fundus photographs and optical coherence tomography (OCT) en face images. We performed a retrospective, comparative study on 46 eyes from 46 glaucoma patients with localized RNFL...
Uloženo v:
| Vydáno v: | Journal of glaucoma Ročník 27; číslo 3; s. 269 |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
United States
01.03.2018
|
| ISSN: | 1536-481X, 1536-481X |
| On-line přístup: | Zjistit podrobnosti o přístupu |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| Abstract | The purpose of this article is to compare the locations of localized retinal nerve fiber layer (RNFL) defects in red-free fundus photographs and optical coherence tomography (OCT) en face images.
We performed a retrospective, comparative study on 46 eyes from 46 glaucoma patients with localized RNFL defects observed in red-free fundus photographs. En face structural images were obtained in the superficial and whole retinal layers using OCT and were overlaid on the corresponding red-free fundus photographs. The proximal/distal angular locations and angular width of each RNFL defect in red-free photos (red-free defects) and in en face structural images (en face defects) were compared.
In the superficial retinal layer, there were no significant differences between red-free and en face defects on the proximal/distal angular location and angular width. In the whole retinal layer, the degree of the distal angular location of the en face defects was significantly larger than that of the red-free defects (71.85±18.26 vs. 70.87±17.90 degrees, P=0.003). The correlations of clinical variables with the differences in angular parameters between red-free and en face defects were not significant in the superficial retinal layer. The average RNFL thickness was negatively correlated with the difference in the distal angular location in the whole retinal layer (Pearson correlation coefficient=-0.401, P=0.006).
Localized RNFL defects detected in OCT en face structural images of the superficial retinal layer showed high topographic correlation with defects detected in red-free photographs. OCT en face structural images in the superficial layer may be an alternative to red-free fundus photography for the identification of localized RNFL defects in glaucomatous eyes. |
|---|---|
| AbstractList | The purpose of this article is to compare the locations of localized retinal nerve fiber layer (RNFL) defects in red-free fundus photographs and optical coherence tomography (OCT) en face images.
We performed a retrospective, comparative study on 46 eyes from 46 glaucoma patients with localized RNFL defects observed in red-free fundus photographs. En face structural images were obtained in the superficial and whole retinal layers using OCT and were overlaid on the corresponding red-free fundus photographs. The proximal/distal angular locations and angular width of each RNFL defect in red-free photos (red-free defects) and in en face structural images (en face defects) were compared.
In the superficial retinal layer, there were no significant differences between red-free and en face defects on the proximal/distal angular location and angular width. In the whole retinal layer, the degree of the distal angular location of the en face defects was significantly larger than that of the red-free defects (71.85±18.26 vs. 70.87±17.90 degrees, P=0.003). The correlations of clinical variables with the differences in angular parameters between red-free and en face defects were not significant in the superficial retinal layer. The average RNFL thickness was negatively correlated with the difference in the distal angular location in the whole retinal layer (Pearson correlation coefficient=-0.401, P=0.006).
Localized RNFL defects detected in OCT en face structural images of the superficial retinal layer showed high topographic correlation with defects detected in red-free photographs. OCT en face structural images in the superficial layer may be an alternative to red-free fundus photography for the identification of localized RNFL defects in glaucomatous eyes. The purpose of this article is to compare the locations of localized retinal nerve fiber layer (RNFL) defects in red-free fundus photographs and optical coherence tomography (OCT) en face images.PURPOSEThe purpose of this article is to compare the locations of localized retinal nerve fiber layer (RNFL) defects in red-free fundus photographs and optical coherence tomography (OCT) en face images.We performed a retrospective, comparative study on 46 eyes from 46 glaucoma patients with localized RNFL defects observed in red-free fundus photographs. En face structural images were obtained in the superficial and whole retinal layers using OCT and were overlaid on the corresponding red-free fundus photographs. The proximal/distal angular locations and angular width of each RNFL defect in red-free photos (red-free defects) and in en face structural images (en face defects) were compared.METHODSWe performed a retrospective, comparative study on 46 eyes from 46 glaucoma patients with localized RNFL defects observed in red-free fundus photographs. En face structural images were obtained in the superficial and whole retinal layers using OCT and were overlaid on the corresponding red-free fundus photographs. The proximal/distal angular locations and angular width of each RNFL defect in red-free photos (red-free defects) and in en face structural images (en face defects) were compared.In the superficial retinal layer, there were no significant differences between red-free and en face defects on the proximal/distal angular location and angular width. In the whole retinal layer, the degree of the distal angular location of the en face defects was significantly larger than that of the red-free defects (71.85±18.26 vs. 70.87±17.90 degrees, P=0.003). The correlations of clinical variables with the differences in angular parameters between red-free and en face defects were not significant in the superficial retinal layer. The average RNFL thickness was negatively correlated with the difference in the distal angular location in the whole retinal layer (Pearson correlation coefficient=-0.401, P=0.006).RESULTSIn the superficial retinal layer, there were no significant differences between red-free and en face defects on the proximal/distal angular location and angular width. In the whole retinal layer, the degree of the distal angular location of the en face defects was significantly larger than that of the red-free defects (71.85±18.26 vs. 70.87±17.90 degrees, P=0.003). The correlations of clinical variables with the differences in angular parameters between red-free and en face defects were not significant in the superficial retinal layer. The average RNFL thickness was negatively correlated with the difference in the distal angular location in the whole retinal layer (Pearson correlation coefficient=-0.401, P=0.006).Localized RNFL defects detected in OCT en face structural images of the superficial retinal layer showed high topographic correlation with defects detected in red-free photographs. OCT en face structural images in the superficial layer may be an alternative to red-free fundus photography for the identification of localized RNFL defects in glaucomatous eyes.CONCLUSIONSLocalized RNFL defects detected in OCT en face structural images of the superficial retinal layer showed high topographic correlation with defects detected in red-free photographs. OCT en face structural images in the superficial layer may be an alternative to red-free fundus photography for the identification of localized RNFL defects in glaucomatous eyes. |
| Author | Yoo, Chungkwon Kim, Yong Yeon Park, Ji-Hye Jung, Jae Hoon |
| Author_xml | – sequence: 1 givenname: Jae Hoon surname: Jung fullname: Jung, Jae Hoon organization: Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea – sequence: 2 givenname: Ji-Hye surname: Park fullname: Park, Ji-Hye – sequence: 3 givenname: Chungkwon surname: Yoo fullname: Yoo, Chungkwon – sequence: 4 givenname: Yong Yeon surname: Kim fullname: Kim, Yong Yeon |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29303874$$D View this record in MEDLINE/PubMed |
| BookMark | eNpNkEtLw0AQgBep2If-A5E9ekndzG6SzVFqWyvFilbxVjab2TaSl7uJUG_-cwNV6BxmBuabD2aGpFdWJRJy6bOxz-LoZvEwH7PjkGF4QgZ-wENPSP-9d9T3ydC5D8aAAfhnpA8xZ1xGYkB-lpVWefaNKX3GJitVTh_RfiGdZQlaulT7Lt-hQd04mpUdlHrGItKnXdVUW6vqnaNvaF3r6LSkM6WRvjS21U1rO9eqbrLOTyfVDi2W3XBdFYe1PV0UaovunJwalTu8-Ksj8jqbrif33nI1X0xul54WAKGnDSqfaQnaD7kJA4EGTHdRCFxEoeBxEqWRApNoQBQmAUAJTAQAmqMUEkbk-uCtbfXZoms2ReY05rkqsWrdxo9lHPBActGhV39omxSYbmqbFcruN_9vg1_12nJY |
| CitedBy_id | crossref_primary_10_1038_s41598_024_59419_3 crossref_primary_10_1016_j_preteyeres_2020_100875 crossref_primary_10_1038_s41433_023_02452_9 crossref_primary_10_1097_IJG_0000000000001388 crossref_primary_10_3390_app11094158 crossref_primary_10_4103_ijo_IJO_601_22 crossref_primary_10_1038_s41598_024_53133_w crossref_primary_10_1016_j_jfma_2020_12_026 crossref_primary_10_1097_IJG_0000000000001528 crossref_primary_10_1371_journal_pone_0229867 |
| ContentType | Journal Article |
| DBID | NPM 7X8 |
| DOI | 10.1097/IJG.0000000000000866 |
| DatabaseName | PubMed MEDLINE - Academic |
| DatabaseTitle | PubMed MEDLINE - Academic |
| DatabaseTitleList | PubMed MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1536-481X |
| ExternalDocumentID | 29303874 |
| Genre | Journal Article |
| GroupedDBID | --- .-D .Z2 0R~ 2V- 53G 5GY 5VS 8L- AAAAV AAHPQ AAIQE AARTV AASCR AAYEP ABASU ABBUW ABDIG ABJNI ABOCM ABVCZ ABXRP ABXVJ ABZAD ACCJW ACDDN ACEWG ACGFO ACGFS ACILI ACWDW ACWRI ACXJB ACXNZ ADFPA ADGGA ADHPY ADNKB AE3 AE6 AEETU AENEX AFDTB AFUWQ AGINI AHQNM AHRYX AHVBC AINUH AJCLO AJIOK AJNWD AJNYG AJZMW AKCTQ ALKUP ALMA_UNASSIGNED_HOLDINGS ALMTX AMJPA AMKUR AMNEI AOHHW AWKKM BQLVK BS7 C45 CS3 DIWNM DU5 DUNZO E.X EBS EEVPB EJD EX3 F2K F2L F5P FCALG FL- GNXGY GQDEL H0~ HLJTE HZ~ IKREB IN~ IPNFZ JK3 JK8 K8S KD2 KMI L-C N9A NPM N~M O9- OCUKA ODA OJAPA OL1 OLG OLV OLW OLZ OPUJH ORVUJ OUVQU OVD OVDNE OXXIT P-K P2P R58 RIG RLZ S4R S4S TEORI TSPGW V2I W3M WOQ WOW X3V X3W YFH ZB8 ZFV ZZMQN 7X8 ABPXF ABZZY ADKSD AFBFQ AOQMC |
| ID | FETCH-LOGICAL-c4226-cfea10c82c163f654ef2f002623476439b7d7a2fbc2ee4fb22e8204522c3e8482 |
| IEDL.DBID | 7X8 |
| ISICitedReferencesCount | 13 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000428803500021&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1536-481X |
| IngestDate | Wed Oct 01 13:48:00 EDT 2025 Wed Feb 19 02:36:32 EST 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 3 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c4226-cfea10c82c163f654ef2f002623476439b7d7a2fbc2ee4fb22e8204522c3e8482 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
| PMID | 29303874 |
| PQID | 1989535834 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_1989535834 pubmed_primary_29303874 |
| PublicationCentury | 2000 |
| PublicationDate | 2018-March |
| PublicationDateYYYYMMDD | 2018-03-01 |
| PublicationDate_xml | – month: 03 year: 2018 text: 2018-March |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Journal of glaucoma |
| PublicationTitleAlternate | J Glaucoma |
| PublicationYear | 2018 |
| SSID | ssj0020221 |
| Score | 2.261962 |
| Snippet | The purpose of this article is to compare the locations of localized retinal nerve fiber layer (RNFL) defects in red-free fundus photographs and optical... |
| SourceID | proquest pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | 269 |
| Title | Localized Retinal Nerve Fiber Layer Defects in Red-free Photographs Versus En Face Structural Optical Coherence Tomography Images |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/29303874 https://www.proquest.com/docview/1989535834 |
| Volume | 27 |
| WOSCitedRecordID | wos000428803500021&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV07T8MwELZ4CbHwfj9kJFaL1nm5E0JAoQhKxUPqVjnOWXRoUpqWgY1_zp3jwsKARIZMthTZF_u7u---Y-wkspGMTF2LhklAhDZIRSpNIBTU0iymUkmdumYTSbutut1GxwfcSk-rnJ6J7qDOCkMx8lPi9kRBpILwbPgmqGsUZVd9C41ZNh8glCFKV9L9ziKgXy-9XmosQlXvTkvnGslp6_a6ki6cPsrrJP4KMt1l01z572eusmUPM_l5ZRdrbAbydbZ47xPpG-zzju6w_gdk_JGKnnFsm7iPvEkMEn6nEYnzS3BcD97PcVAm7AiAd16LcaVyXXKKtU1KfpXzpjbAn5wULcl48IehC5FzKv5w5YT8uRh4cWzeGuAZVm6yl-bV88WN8N0YhKFqW2Es6HrNKGkQwtk4CsFKSy6cDMKEcE2aZImWNjUSILSplKCkE2w3AahQyS02lxc57DCexGgG6AvFOkpxIrp8sc407YJGtKRqu-x4urg9tHZKYegciknZ-1neXbZd7VBvWMly9BC4UC4-3PvD7H22hMhHVWSyAzZv8V-HQ7Zg3sf9cnTkzAjf7c79Fy9t0N0 |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Localized+Retinal+Nerve+Fiber+Layer+Defects+in+Red-free+Photographs+Versus+En+Face+Structural+Optical+Coherence+Tomography+Images&rft.jtitle=Journal+of+glaucoma&rft.au=Jung%2C+Jae+Hoon&rft.au=Park%2C+Ji-Hye&rft.au=Yoo%2C+Chungkwon&rft.au=Kim%2C+Yong+Yeon&rft.date=2018-03-01&rft.eissn=1536-481X&rft.volume=27&rft.issue=3&rft.spage=269&rft_id=info:doi/10.1097%2FIJG.0000000000000866&rft_id=info%3Apmid%2F29303874&rft_id=info%3Apmid%2F29303874&rft.externalDocID=29303874 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1536-481X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1536-481X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1536-481X&client=summon |