Atlas‐guided brain projection tracts: From regions of interest to tractography 3D rendering

The use of diffusion tensor imaging (DTI) has seen significant development over the last two decades, in particular with the development of the tractography of association tracts for preoperative planning of surgery. However, projection tracts are difficult to differentiate from one another and trac...

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Veröffentlicht in:Journal of anatomy Jg. 246; H. 5; S. 732 - 744
Hauptverfasser: Dauleac, Corentin, Mertens, Patrick, Frindel, Carole, Jacquesson, Timothée, Cotton, François
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England Wiley Subscription Services, Inc 01.05.2025
Wiley
Schlagworte:
Adult
Anterior commissure
Atlases as Topic
brain
Brain - anatomy & histology
Cerebellum
diffusion tensor imaging
Diffusion Tensor Imaging - methods
Dorsal columns
Female
Human health and pathology
Humans
Imaging, Three-Dimensional - methods
Life Sciences
Magnetic resonance imaging
Male
Middle Aged
Neural Pathways - anatomy & histology
Neuroimaging
projection tracts
Prospective Studies
Pyramidal tracts
Red nucleus
region of interest
Rubrospinal tract
Spinal cord
Spinocerebellar tract
Spinothalamic tract
Tissues and Organs
tractography
Young Adult
diffusion tensor imaging
tractography
brain
atlas
projection tracts
region of interest
ISSN:0021-8782, 1469-7580, 1469-7580
Online-Zugang:Volltext
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Zusammenfassung:The use of diffusion tensor imaging (DTI) has seen significant development over the last two decades, in particular with the development of the tractography of association tracts for preoperative planning of surgery. However, projection tracts are difficult to differentiate from one another and tractography studies have failed to reconstruct these ascending/descending pathways from/to the spinal cord. The present study proposes an atlas of regions of interest (ROIs) designed specifically for projection tracts tractography. Forty‐nine healthy subjects were included in this prospective study. Brain DTI was acquired using the same 3 T MRI scanner, with 32 diffusion directions. Distortions were corrected using the FSL software package. ROIs were drawn using the anterior commissure (AC)–posterior commissure (PC) line on the following landmarks: the pyramid for the corticospinal tract, the medio‐caudal part of the red nucleus for the rubrospinal tract, the pontine reticular nucleus for corticoreticular tract, the superior and inferior cerebellar peduncles for, respectively, the anterior and posterior spinocerebellar tract, the gracilis and cuneatus nucleus for the dorsal columns, and the ventro‐posterolateral nucleus for the spinothalamic tract. Fiber tracking was performed using a deterministic algorithm using DSI Studio software. ROI coordinates, according to AC–PC line, were given for each tract. Tractography was obtained for each tract, allowing tridimensional rendering and comparison of tracking metrics between tracts. The present study reports the accurate design of specific ROIs for tractography of each projection tract. This could be a useful tool in order to differentiate projection tracts at the spinal cord level. The present study proposes an atlas of regions of interest (ROIs) designed specifically for projection tracts tractography. ROIs were drawn using the anterior commissure (AC)–posterior commissure (PC) line. Fiber tracking was performed using a deterministic algorithm using DSI Studio software. ROI coordinates, according to AC‐PC line, were given for each tract. Tractography was obtained for each tract, allowing tridimensional rendering and comparison of tracking metrics between tracts.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0021-8782
1469-7580
1469-7580
DOI:10.1111/joa.14120