Potential drug targets for multiple sclerosis identified through Mendelian randomization analysis

Abstract Multiple sclerosis is a complex autoimmune disease, and several therapies for multiple sclerosis have been developed and widely used. However, existing medications for multiple sclerosis were far from satisfactory due to their failure to suppress relapses and alleviate disease progression....

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Vydáno v:	Brain (London, England : 1878) Ročník 146; číslo 8; s. 3364 - 3372
Hlavní autoři:	Lin, Jianfeng, Zhou, Jiawei, Xu, Yan
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	US Oxford University Press 01.08.2023
Témata:	Bayes Theorem Genome-Wide Association Study Humans Mendelian Randomization Analysis Multiple Sclerosis - drug therapy Multiple Sclerosis - genetics Phenotype Polymorphism, Single Nucleotide - genetics multiple sclerosis drug target Mendelian randomization
ISSN:	0006-8950, 1460-2156, 1460-2156
On-line přístup:	Získat plný text
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