The Genetic Basis of Thyroid Function: Novel Findings and New Approaches

Genetic factors are major determinants of thyroid function. Over the last two decades, multiple genetic variants have been associated with variations in normal range thyroid function tests. Most recently, a large-scale genome-wide association study (GWAS) doubled the number of known variants associa...

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Vydáno v:	The journal of clinical endocrinology and metabolism Ročník 105; číslo 6; s. 1707 - 1721
Hlavní autoři:	Kuś, Aleksander, Chaker, Layal, Teumer, Alexander, Peeters, Robin P, Medici, Marco
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Oxford University Press 01.06.2020
Témata:	Biomarkers - analysis Genetic diversity Genetic factors Genetic Linkage Genome-wide association studies Genome-Wide Association Study Genomes Genotype Health aspects Humans Hypothalamic-pituitary-thyroid axis Hypothalamus Identification and classification Methods Observations Pituitary Polymorphism, Single Nucleotide Prognosis Thyroid diseases Thyroid Diseases - blood Thyroid Diseases - genetics Thyroid Diseases - physiopathology Thyroid gland Thyroid Gland - physiology Thyroid gland function tests Thyroid Hormones - blood Thyroid-stimulating hormone Thyrotropin Thyroxine Netherlands TSH genetics thyroid single nucleotide polymorphism FT4 genome-wide association study
ISSN:	0021-972X, 1945-7197, 1945-7197
On-line přístup:	Získat plný text
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