Programming gene and engineered-cell therapies with synthetic biology

Gene and engineered-cell therapies promise to treat diseases by genetically modifying cells to carry out therapeutic tasks. Although the field has had some success in treating monogenic disorders and hematological malignancies, current approaches are limited to overexpression of one or a few transge...

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Vydané v:	Science (American Association for the Advancement of Science) Ročník 359; číslo 6376
Hlavní autori:	Kitada, Tasuku, DiAndreth, Breanna, Teague, Brian, Weiss, Ron
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 09.02.2018
Predmet:	Cell Engineering - methods Cell- and Tissue-Based Therapy Cellular Reprogramming Techniques DNA - genetics Gene Expression Gene Regulatory Networks Genes, Synthetic Genetic Engineering - methods Genetic Therapy Humans Recombinant Fusion Proteins RNA - genetics Synthetic Biology - methods Transgenes
ISSN:	1095-9203, 1095-9203
On-line prístup:	Zistit podrobnosti o prístupe
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