Programming gene and engineered-cell therapies with synthetic biology

Gene and engineered-cell therapies promise to treat diseases by genetically modifying cells to carry out therapeutic tasks. Although the field has had some success in treating monogenic disorders and hematological malignancies, current approaches are limited to overexpression of one or a few transge...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) Jg. 359; H. 6376
Hauptverfasser:	Kitada, Tasuku, DiAndreth, Breanna, Teague, Brian, Weiss, Ron
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 09.02.2018
Schlagworte:	Cell Engineering - methods Cell- and Tissue-Based Therapy Cellular Reprogramming Techniques DNA - genetics Gene Expression Gene Regulatory Networks Genes, Synthetic Genetic Engineering - methods Genetic Therapy Humans Recombinant Fusion Proteins RNA - genetics Synthetic Biology - methods Transgenes
ISSN:	1095-9203, 1095-9203
Online-Zugang:	Weitere Angaben
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