Bacteriophage‐antibiotic combination therapy for multidrug‐resistant Pseudomonas aeruginosa: In vitro synergy testing

Aims Here, we investigate the impact of phage‐antibiotic combinations (PAC) on bacterial killing, resistance development and outer membrane vesicle (OMV) production in multidrug‐resistant (MDR) P. aeruginosa. Methods and Results After screening 10 well‐characterized MDR P. aeruginosa strains against...

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Vydané v:	Journal of applied microbiology Ročník 133; číslo 3; s. 1636 - 1649
Hlavní autori:	Holger, Dana J., Lev, Katherine L., Kebriaei, Razieh, Morrisette, Taylor, Shah, Rahi, Alexander, Jose, Lehman, Susan M., Rybak, Michael J.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Oxford University Press 01.09.2022
Predmet:	Antibiotic resistance Antibiotics Bacteria bacteriophages Ciprofloxacin Colistin Combination therapy Drug resistance Host range In vivo methods and tests Meropenem Minimum inhibitory concentration Multidrug resistant organisms multiple drug resistance Parameter identification Phages Pharmacodynamics Pharmacokinetics Pharmacology Pseudomonas aeruginosa Reduction Strains (organisms) synergism therapeutics
ISSN:	1364-5072, 1365-2672, 1365-2672
On-line prístup:	Získať plný text
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