Bacteriophage‐antibiotic combination therapy for multidrug‐resistant Pseudomonas aeruginosa: In vitro synergy testing

Aims Here, we investigate the impact of phage‐antibiotic combinations (PAC) on bacterial killing, resistance development and outer membrane vesicle (OMV) production in multidrug‐resistant (MDR) P. aeruginosa. Methods and Results After screening 10 well‐characterized MDR P. aeruginosa strains against...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of applied microbiology Vol. 133; no. 3; pp. 1636 - 1649
Main Authors:	Holger, Dana J., Lev, Katherine L., Kebriaei, Razieh, Morrisette, Taylor, Shah, Rahi, Alexander, Jose, Lehman, Susan M., Rybak, Michael J.
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01.09.2022
Subjects:	Antibiotic resistance Antibiotics Bacteria bacteriophages Ciprofloxacin Colistin Combination therapy Drug resistance Host range In vivo methods and tests Meropenem Minimum inhibitory concentration Multidrug resistant organisms multiple drug resistance Parameter identification Phages Pharmacodynamics Pharmacokinetics Pharmacology Pseudomonas aeruginosa Reduction Strains (organisms) synergism therapeutics
ISSN:	1364-5072, 1365-2672, 1365-2672
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!