Convergent evolution and B-cell recirculation in germinal centers in a human lymph node

Germinal centers (GCs) play a central role in generating an effective immune response against infectious pathogens, and failures in their regulating mechanisms can lead to the development of autoimmune diseases and cancer. Although previous works study experimental systems of the immune response wit...

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Bibliographic Details
Published in:	Life science alliance Vol. 6; no. 11; p. e202301959
Main Authors:	Pelissier, Aurelien, Stratigopoulou, Maria, Donner, Naomi, Dimitriadis, Evangelos, Bende, Richard J, Guikema, Jeroen E, Rodriguez Martinez, Maria, van Noesel, Carel JM
Format:	Journal Article
Language:	English
Published:	United States Life Science Alliance 01.11.2023 Life Science Alliance LLC
Subjects:	Animal models Animals Antigens Autoimmune Diseases B-Lymphocytes Cloning Competitive advantage Germinal Center Germinal centers Humans Immunization Lymph Nodes Lymphatic system Lymphocytes B Mice Mutation Phylogeny Reproducibility
ISSN:	2575-1077, 2575-1077
Online Access:	Get full text
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