Epigenetics and cancer

Epigenetic mechanisms act to change the accessibility of chromatin to transcriptional regulation locally and globally via modifications of the DNA and by modification or rearrangement of nucleosomes. Epigenetic gene regulation collaborates with genetic alterations in cancer development. This is evid...

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Bibliographic Details
Published in:Genes & development Vol. 18; no. 19; p. 2315
Main Authors: Lund, Anders H, van Lohuizen, Maarten
Format: Journal Article
Language:English
Published: United States 01.10.2004
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ISSN:0890-9369
Online Access:Get more information
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