N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis

Circular RNAs (circRNAs) have been implicated in cancer progression through largely unknown mechanisms. Herein, we identify an N 6 -methyladenosine (m 6 A) modified circRNA, circNSUN2, frequently upregulated in tumor tissues and serum samples from colorectal carcinoma (CRC) patients with liver metas...

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Vydané v:	Nature communications Ročník 10; číslo 1; s. 4695
Hlavní autori:	Chen, Ri-Xin, Chen, Xin, Xia, Liang-Ping, Zhang, Jia-Xing, Pan, Zhi-Zhong, Ma, Xiao-Dan, Han, Kai, Chen, Jie-Wei, Judde, Jean-Gabrie, Deas, Olivier, Wang, Feng, Ma, Ning-Fang, Guan, Xinyuan, Yun, Jing-Ping, Wang, Feng-Wei, Xu, Rui-Hua, Dan Xie
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London Nature Publishing Group UK 16.10.2019
Predmet:	13/109 13/89 14/1 14/19 14/32 14/5 38/88 38/91 631/337/1645/2570 631/337/384 631/67/322 631/80/84 64/60 82/58 82/83 Humanities and Social Sciences multidisciplinary Science Science (multidisciplinary)
ISSN:	2041-1723, 2041-1723
On-line prístup:	Získať plný text
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