New insights on circumscribed choroidal hemangioma: “bench to bedside”

Circumscribed choroidal hemangioma is a rare vascular hamartoma of the choroid, presenting as a red–orange mass at the posterior pole on fundoscopic examination. Despite its benign origin, associated complications such as subretinal fluid, serous retinal detachment, retinoschisis and neovascular gla...

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Vydáno v:	Graefe's archive for clinical and experimental ophthalmology Ročník 262; číslo 4; s. 1093 - 1110
Hlavní autoři:	Lupidi, Marco, Centini, Chiara, Castellucci, Greta, Nicolai, Michele, Lassandro, Nicola, Cagini, Carlo, Rizzo, Clara, Chhablani, Jay, Mariotti, Cesare
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Berlin/Heidelberg Springer Berlin Heidelberg 01.04.2024 Springer Nature B.V
Témata:	Acuity Angiography Choroid - pathology Choroid Neoplasms - diagnosis Choroid Neoplasms - therapy Differential diagnosis Fluorescein Angiography Glaucoma Hemangioma Hemangioma - diagnosis Hemangioma - pathology Hemangioma - therapy Humans Medical imaging Medicine Medicine & Public Health Melanoma Metastases Neoplasia Ophthalmology Photochemotherapy Photodynamic therapy Radiation therapy Retinoschisis Review Article Thermotherapy Tomography Tomography, Optical Coherence Vascular endothelial growth factor Indocyanine green angiography OCT Circumscribed choroidal hemangioma Photodynamic therapy Subretinal fluid Choroidal hemangioma
ISSN:	0721-832X, 1435-702X, 1435-702X
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Popis
Shrnutí:	Circumscribed choroidal hemangioma is a rare vascular hamartoma of the choroid, presenting as a red–orange mass at the posterior pole on fundoscopic examination. Despite its benign origin, associated complications such as subretinal fluid, serous retinal detachment, retinoschisis and neovascular glaucoma may lead to serious visual impairment in more than half patients. Because of its similarity to amelanotic choroidal melanoma and choroidal metastasis, differential diagnosis is still challenging for specialists. Multimodal imaging such as ultrasonography, fluorescein angiography, indocyanine green angiography, optical coherence tomography, and optical coherence tomography angiography guides the clinician to the correct diagnosis and the proper follow-up. Treatment is indicated in symptomatic cases in order to resolve exudation and improve visual acuity. Treatment options include photocoagulation, transpupillary thermotherapy, radiation therapy, photodynamic therapy and anti-vascular endothelial growth factor therapy. Currently, photodynamic therapy is the treatment of choice due to its effectiveness and safety. The purpose of this review is to describe the latest knowledge in the etiopathogenesis of the circumscribed choroidal hemangioma, the most recent multimodal imaging findings, and the available treatment options.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23
ISSN:	0721-832X 1435-702X 1435-702X
DOI:	10.1007/s00417-023-06179-x