ESGO/ESTRO/ESP Guidelines for the management of patients with endometrial carcinoma

A European consensus conference on endometrial carcinoma was held in 2014 to produce multidisciplinary evidence-based guidelines on selected questions. Given the large body of literature on the management of endometrial carcinoma published since 2014, the European Society of Gynaecological Oncology...

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Vydáno v:Virchows Archiv : an international journal of pathology Ročník 478; číslo 2; s. 153 - 190
Hlavní autoři: Concin, Nicole, Creutzberg, Carien L., Vergote, Ignace, Cibula, David, Mirza, Mansoor Raza, Marnitz, Simone, Ledermann, Jonathan A., Bosse, Tjalling, Chargari, Cyrus, Fagotti, Anna, Fotopoulou, Christina, González-Martín, Antonio, Lax, Sigurd F., Lorusso, Domenica, Marth, Christian, Morice, Philippe, Nout, Remi A., O’Donnell, Dearbhaile E., Querleu, Denis, Raspollini, Maria Rosaria, Sehouli, Jalid, Sturdza, Alina E., Taylor, Alexandra, Westermann, Anneke M., Wimberger, Pauline, Colombo, Nicoletta, Planchamp, François, Matias-Guiu, Xavier
Médium: Journal Article
Jazyk:angličtina
Vydáno: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2021
Springer Nature B.V
Témata:
Biomarkers, Tumor - genetics
Biopsy - standards
Cancer
Carcinoma
Carcinoma - genetics
Carcinoma - pathology
Carcinoma - therapy
Endometrial cancer
Endometrial Neoplasms - genetics
Endometrial Neoplasms - pathology
Endometrial Neoplasms - therapy
Endometrium
Evidence-Based Medicine - standards
Female
Fertility
Group dynamics
Guidelines
Humans
Leadership
Medical Oncology - standards
Medicine
Medicine & Public Health
Metastases
Molecular Diagnostic Techniques - standards
Neoplasm Staging - standards
Oncology
Original Article
Pathology
Predictive Value of Tests
Radiation therapy
Risk Assessment
Risk Factors
Risk groups
Treatment Outcome
Uterine cancer
Europe
Molecular markers
Management
Staging
Endometrial carcinoma
Guidelines
ISSN:0945-6317, 1432-2307, 1432-2307
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Shrnutí:A European consensus conference on endometrial carcinoma was held in 2014 to produce multidisciplinary evidence-based guidelines on selected questions. Given the large body of literature on the management of endometrial carcinoma published since 2014, the European Society of Gynaecological Oncology (ESGO), the European SocieTy for Radiotherapy & Oncology (ESTRO) and the European Society of Pathology (ESP) jointly decided to update these evidence-based guidelines and to cover new topics in order to improve the quality of care for women with endometrial carcinoma across Europe and worldwide. ESGO/ESTRO/ESP nominated an international multidisciplinary development group consisting of practicing clinicians and researchers who have demonstrated leadership and expertise in the care and research of endometrial carcinoma (27 experts across Europe). To ensure that the guidelines are evidence-based, the literature published since 2014, identified from a systematic search was reviewed and critically appraised. In the absence of any clear scientific evidence, judgment was based on the professional experience and consensus of the development group. The guidelines are thus based on the best available evidence and expert agreement. Prior to publication, the guidelines were reviewed by 191 independent international practitioners in cancer care delivery and patient representatives. The guidelines comprehensively cover endometrial carcinoma staging, definition of prognostic risk groups integrating molecular markers, pre- and intra-operative work-up, fertility preservation, management for early, advanced, metastatic, and recurrent disease and palliative treatment. Principles of radiotherapy and pathological evaluation are also defined.
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ISSN:0945-6317
1432-2307
1432-2307
DOI:10.1007/s00428-020-03007-z