An overview of key industrial product citric acid production by Aspergillus niger and its application

Abstract   Citric acid possesses high economic value and is considered as the world’s largest consumed organic acid in numerous industries. Citric acid applications range from food to beverage industries, pharmaceuticals, cosmetics, and the environment. It is mostly produced by microbial fermentatio...

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Vydáno v:Journal of industrial microbiology & biotechnology Ročník 52
Hlavní autoři: Latif, Ambreen, Hassan, Noor, Ali, Hazrat, Niazi, Muhammad Bilal Khan, Jahan, Zaib, Ghuman, Iqra Latif, Hassan, Farwa, Saqib, Anam
Médium: Journal Article
Jazyk:angličtina
Vydáno: Germany Oxford University Press 28.03.2025
Témata:
Aspergillus niger - genetics
Aspergillus niger - metabolism
Biotechnology - methods
Citric Acid - metabolism
Fermentation
Industrial Microbiology - methods
Industry
Molecular biology
Fermentation
Citric acid
A. niger
ISSN:1367-5435, 1476-5535, 1476-5535
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Shrnutí:Abstract   Citric acid possesses high economic value and is considered as the world’s largest consumed organic acid in numerous industries. Citric acid applications range from food to beverage industries, pharmaceuticals, cosmetics, and the environment. It is mostly produced by microbial fermentation, but Aspergillus niger is considered as the main workhorse for large-scale production of citric acid. In the current review, special devotion has been made toward addressing the latest and innovative literature related to production of citric acid by A. niger. The review article discusses A. niger historical involvement in citric acid production, fermentation technologies, molecular biology, biosynthesis, accumulation of citric acid, methods for enhanced production of citric acid, different operational factors also influencing citric acid production, and various techniques used for citric acid recovery. Also, copious biotechnological applications of citric acid are summarized for a fundamental comprehension of the subject and its critical role in diverse fields of industries. One-Sentence Summary This review describes the historical role of Aspergillus niger in the production of citric acid, fermentation technologies, molecular biology, techniques for increased citric acid production, and other physical and chemical variables influencing the production of citric acid. Graphical Abstract Graphical Abstract
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ISSN:1367-5435
1476-5535
1476-5535
DOI:10.1093/jimb/kuaf007