Crystal Structure of the Bacteriophage Qβ Coat Protein in Complex with the RNA Operator of the Replicase Gene

The coat proteins of single-stranded RNA bacteriophages specifically recognize and bind to a hairpin structure in their genome at the beginning of the replicase gene. The interaction serves to repress the synthesis of the replicase enzyme late in infection and contributes to the specific encapsidati...

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Bibliographic Details
Published in:	Journal of molecular biology Vol. 426; no. 5; pp. 1039 - 1049
Main Authors:	Rumnieks, Janis, Tars, Kaspars
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 06.03.2014
Subjects:	adenine allolevivirus Bacteria bacteriophages binding proteins Capsid Proteins - chemistry Capsid Proteins - genetics Capsid Proteins - metabolism coat proteins coevolution crystal structure Crystallography, X-Ray genes Leviviridae Models, Molecular Nucleic Acid Conformation Operator Regions, Genetic - genetics Phage MS2 Protein Binding Protein Conformation protein–RNA interaction RNA RNA recognition RNA Replicase - chemistry RNA Replicase - genetics RNA Replicase - metabolism RNA, Viral - chemistry RNA, Viral - genetics RNA, Viral - metabolism translational repression tyrosine RNA recognition Leviviridae translational repression protein–RNA interaction allolevivirus
ISSN:	0022-2836, 1089-8638, 1089-8638
Online Access:	Get full text
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