Eosinophil extracellular traps activate type 2 innate lymphoid cells through stimulating airway epithelium in severe asthma

Background Activated eosinophils release extracellular traps (EETs), which contribute to airway inflammation in severe asthma (SA). However, the role of EETs in innate immunity has not yet been completely determined. The present study aimed to demonstrate the mechanism of airway inflammation in SA m...

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Bibliographic Details
Published in:	Allergy (Copenhagen) Vol. 75; no. 1; pp. 95 - 103
Main Authors:	Choi, Youngwoo, Kim, Young‐Min, Lee, Hee‐Ra, Mun, Jiyeong, Sim, Soyoon, Lee, Dong‐Hyun, Pham, Duy Le, Kim, Seung‐Hyun, Shin, Yoo Seob, Lee, Seung‐Woo, Park, Hae‐Sim
Format:	Journal Article
Language:	English
Published:	Denmark Blackwell Publishing Ltd 01.01.2020
Subjects:	Adult Aged Alveoli Animals Asthma Asthma - immunology Bronchus eosinophils Eosinophils - immunology Epithelium extracellular traps Extracellular Traps - immunology Female Humans Immune response Innate immunity innate lymphoid cells Leukocytes (eosinophilic) Lymphocyte Subsets - immunology Lymphocytes - immunology Lymphoid cells Male Mice Mice, Inbred BALB C Middle Aged RAG1 protein Respiratory Mucosa - immunology Respiratory tract Respiratory tract diseases severe asthma Thymic stromal lymphopoietin Traps severe asthma eosinophils extracellular traps epithelium innate lymphoid cells
ISSN:	0105-4538, 1398-9995, 1398-9995
Online Access:	Get full text
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