NEAT1 contributes to neuropathic pain development through targeting miR‐381/HMGB1 axis in CCI rat models

LncRNAs have been recognized as significant regulators in various diseases including neuropathic pain. Although the lncRNA NEAT1 has been reported to be involved in multiple cancers, its biological functions in neuropathic pain still remain unknown. In our present study, a chronic constriction injur...

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Veröffentlicht in:	Journal of cellular physiology Jg. 233; H. 9; S. 7103 - 7111
Hauptverfasser:	Xia, Lie‐Xin, Ke, Chengming, Lu, Jing‐Min
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Wiley Subscription Services, Inc 01.09.2018
Schlagworte:	Animal models Bioinformatics HMGB1 HMGB1 protein Hyperalgesia IL-1β Inflammation Mechanical properties miRNA miR‐381 NEAT1 Neuralgia neuropathic pain Pain Pain perception Rats Regulators Ribonucleic acid RNA Rodents Spinal cord Tumor necrosis factor Tumor necrosis factor-TNF miR-381 neuropathic pain HMGB1 NEAT1
ISSN:	0021-9541, 1097-4652, 1097-4652
Online-Zugang:	Volltext
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