Post-transcriptional regulation of lipoprotein receptors by the E3-ubiquitin ligase inducible degrader of the low-density lipoprotein receptor

The hepatic low-density lipoprotein receptor (LDLR) pathway is essential for clearing circulating LDL and is an important therapeutic target for treating cardiovascular disease. Abundance of the LDLR is subject to both transcriptional and nontranscriptional control. Here, we highlight a new post-tra...

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Vydané v:	Current opinion in lipidology Ročník 23; číslo 3; s. 213
Hlavní autori:	Sorrentino, Vincenzo, Zelcer, Noam
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 01.06.2012
Predmet:	Animals Humans Lipoproteins, LDL - metabolism Low Density Lipoprotein Receptor-Related Protein-1 - metabolism Proteolysis Receptors, LDL - genetics Receptors, LDL - metabolism Transcription, Genetic Ubiquitin-Protein Ligases - genetics Ubiquitin-Protein Ligases - metabolism
ISSN:	1473-6535, 1473-6535
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