Sputum DNA sequencing in cystic fibrosis: non-invasive access to the lung microbiome and to pathogen details

Background Cystic fibrosis (CF) is a life-threatening genetic disorder, characterized by chronic microbial lung infections due to abnormally viscous mucus secretions within airways. The clinical management of CF typically involves regular respiratory-tract cultures in order to identify pathogens and...

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Veröffentlicht in:	Microbiome Jg. 5; H. 1; S. 20
Hauptverfasser:	Feigelman, Rounak, Kahlert, Christian R., Baty, Florent, Rassouli, Frank, Kleiner, Rebekka L., Kohler, Philipp, Brutsche, Martin H., von Mering, Christian
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 10.02.2017 Springer Nature B.V
Schlagworte:	Bacteria - genetics Bacteria - isolation & purification Bacteria - pathogenicity Bioinformatics Biomedical and Life Sciences Biomedicine Cystic Fibrosis - microbiology Drug Resistance, Bacterial - genetics Genetic Variation Genomic Islands High-Throughput Nucleotide Sequencing Humans Lung - microbiology Medical Microbiology Metagenome Metagenomics Microbial Ecology Microbial Genetics and Genomics Microbiology Microbiota - genetics Multilocus Sequence Typing Respiratory Tract Infections - microbiology Sputum - microbiology Virology WGS metagenomic sequencing Cystic fibrosis Sputum Lung metagenome COPD
ISSN:	2049-2618, 2049-2618
Online-Zugang:	Volltext
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