Averting a malaria disaster

As treatments loose their effectiveness, morbidity and mortality from malaria will inevitably continue to rise. The rationale for combining drugs with independent modes of action is examined.

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Bibliographic Details
Published in:The Lancet (British edition) Vol. 353; no. 9168; pp. 1965 - 1967
Main Authors: White, NJ, Nosten, F, Looareesuwan, S, Watkins, WM, Marsh, K, Snow, RW, Kokwaro, G, Ouma, J, Hien, TT, Molyneux, ME, Taylor, TE, Newbold, CI, Ruebush, TK, Danis, M, Greenwood, BM, Anderson, RM, Olliaro, P
Format: Journal Article
Language:English
Published: London Elsevier Ltd 05.06.1999
Lancet
Elsevier Limited
Subjects:
Animals
Antimalarials - economics
Antimalarials - therapeutic use
Artemisinins
Biological and medical sciences
Costs and Cost Analysis
Drug Resistance
Drug therapy
Drug Therapy, Combination
Drugs, Chinese Herbal - therapeutic use
Human protozoal diseases
Humans
Infectious diseases
Malaria
Malaria, Falciparum - drug therapy
Malaria, Falciparum - epidemiology
Malaria, Falciparum - prevention & control
Medical research
Medical sciences
Parasitic diseases
Protozoal diseases
Pyrimethamine - therapeutic use
Sesquiterpenes - therapeutic use
Sulfadoxine - therapeutic use
Tropical medicine
Vector-borne diseases
Epidemic
Human
Antimalarial
Protozoal disease
Chemoprophylaxis
Costs
Malaria
Toxicity
Artemisinin
Parasitosis
Infection
Prevention
Resistance
Treatment
Parasiticid
ISSN:0140-6736, 1474-547X
Online Access:Get full text
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Description
Summary:As treatments loose their effectiveness, morbidity and mortality from malaria will inevitably continue to rise. The rationale for combining drugs with independent modes of action is examined.
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ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(98)07367-X